SCHEMBL23877491

SCHEMBL23877491

O=C(NC12CC(C(F)(F)F)(C1)C2)c1ccc(C(F)(F)F)cc1NS(=O)(=O)c1ccc(-n2cnnn2)cc1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.45
▸ KMT2A Q03164 1/20 0.45
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ KDM1A O60341 1/20 0.42
▸ USP2 O75604 4/20 0.42
▸ USP8 P40818 4/20 0.42
▸ ACLY P53396 3/20 0.42
▸ MCL1 Q07820 1/20 0.42
▸ USP36 Q9P275 1/20 0.41
▸ NSD2 O96028 1/20 0.39
▸ DUSP3 P51452 1/20 0.39
▸ PTPN5 P54829 1/20 0.39
▸ PTPN11 Q06124 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ ERAP1 Q9NZ08 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30547568 1.00 MEN1 (0.45) MEN1KMT2AL3MBTL1KDM1AUSP2
SCHEMBL23877468 0.90 USP2 (0.44) MEN1KMT2AL3MBTL1KDM1AUSP2
SCHEMBL31046840 0.90 USP2 (0.44) MEN1KMT2AL3MBTL1KDM1AUSP2
SCHEMBL23877535 0.84 KDM1A (0.48) MEN1KMT2AKDM1AUSP2USP8
SCHEMBL23879636 0.83 KDM1A (0.50) MEN1KMT2AL3MBTL1KDM1AUSP2
SCHEMBL31046884 0.83 KDM1A (0.50) L3MBTL1KDM1AUSP2USP8ACLY
SCHEMBL23877472 0.83 KDM1A (0.50) L3MBTL1KDM1AUSP2USP8ACLY
SCHEMBL23877433 0.82 KDM1A (0.49) KDM1AUSP2USP8ACLYUSP36
SCHEMBL23877473 0.82 KDM1A (0.49) L3MBTL1KDM1AUSP2USP8ACLY
SCHEMBL23877479 0.82 KDM1A (0.49) L3MBTL1KDM1AUSP2USP8ACLY

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12606522-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives ORSOBIO, INC. (US) 2026-04-21 — — US disclosed
US-20240409508-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES ORSOBIO, INC. 2024-12-12 — — US disclosed
US-12049439-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives ORSOBIO, INC. (US) 2024-07-30 — — US disclosed
EP-3796975-B1 SULFONYLAMINOBENZAMIDE DERIVATIVES ORSOBIO INC (US) 2023-08-30 — — EP disclosed
EP-3796975-B1 SULFONYLAMINOBENZAMIDE DERIVATIVES ORSOBIO INC (US) 2023-08-30 — — EP disclosed
US-20220055985-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES GILEAD SCIENCES, INC. 2022-02-24 — — US disclosed
US-20220055985-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES GILEAD SCIENCES, INC. 2022-02-24 — — US disclosed
US-11136290-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives THE LIVER COMPANY INC. (US) 2021-10-05 — — US disclosed
US-11136290-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives THE LIVER COMPANY INC. (US) 2021-10-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220055985-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES STS, SULT2A1, SCN2B MEN1 1634/4885KMT2A 1234/4885L3MBTL1 4732/4885
US-12049439-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives STS, SULT2A1, SCN2B MEN1 1634/4885KMT2A 1234/4885L3MBTL1 4732/4885
US-12606522-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives NR3C2, NR5A1, SRD5A2 MEN1 3346/4885KMT2A 2071/4885L3MBTL1 3102/4885
US-20240409508-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES STS, SULT2A1, SCN2B MEN1 1634/4885KMT2A 1234/4885L3MBTL1 4732/4885
US-11136290-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives STS, SULT2A1, SCN2B MEN1 1634/4885KMT2A 1234/4885L3MBTL1 4732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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