Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 4/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16291053 | 0.77 | HTT (0.62) | ATMKDRHTT | |
| SCHEMBL10602253 | 0.75 | CYP11B1 (0.53) | CYP11B1CYP11B2DYRK1AATMF2 | |
| SCHEMBL278161 | 0.74 | TDP1 (0.54) | CYP11B1CYP11B2HTT | |
| SCHEMBL20128445 | 0.73 | FABP4 (0.41) | BACE1HTTHCAR1 | |
| SCHEMBL20698048 | 0.73 | PARP1 (0.34) | DYRK1AHTT | |
| SCHEMBL11988767 | 0.72 | POLB (0.64) | CYP11B1CYP11B2ATMKDRHTT | |
| SCHEMBL17231488 | 0.71 | DYRK1A (0.55) | CYP11B1CYP11B2DYRK1AMAP4K4BRD4 | |
| SCHEMBL17691821 | 0.70 | DYRK1A (0.57) | CYP11B1CYP11B2DYRK1ABACE1BRD4 | |
| SCHEMBL31144784 | 0.69 | HTT (0.51) | ATMKDRHTT | |
| SCHEMBL18609345 | 0.69 | FGFR1 (0.56) | ATMKDRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3888147-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | Merck Patent GmbH (DE) | 2021-10-06 | — | — | EP | disclosed |