Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | STAT6 | P42226 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30744769 | 0.98 | TDP1 (0.52) | TDP1HTTSMN1; SMN2LMNASTAT6 | |
| Decane SCHEMBL9491454 | 0.87 | ASAH1 (0.54) | TDP1HTTSMN1; SMN2LMNACYP11B1 | |
| SCHEMBL7196401 | 0.75 | TDP1 (0.58) | TDP1HTTSMN1; SMN2LMNASTAT6 | |
| SCHEMBL3417306 | 0.74 | HTT (0.73) | TDP1HTTPOLBFGFR1 | |
| SCHEMBL23877945 | 0.74 | CYP11B1 (0.45) | HTTCYP11B1CYP11B2 | |
| SCHEMBL22617807 | 0.74 | MAPT (0.33) | TDP1FGFR1HSD17B10 | |
| SCHEMBL2489876 | 0.73 | TDP1 (0.56) | TDP1HTTSMN1; SMN2LMNASTAT6 | |
| SCHEMBL7555734 | 0.73 | HTT (0.53) | TDP1HTTSMN1; SMN2LMNASTAT6 | |
| SCHEMBL5399 | 0.71 | TDP1 (0.59) | TDP1HTTSMN1; SMN2LMNACYP11B1 | |
| SCHEMBL277760 | 0.71 | TDP1 (0.54) | TDP1HTTSMN1; SMN2LMNASTAT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1843 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119059958-A | Method for aryl debromination acylation of bromobenzazepine compounds | 上海沃凯生物技术有限公司 | 2024-12-03 | — | — | CN | claimed |
| CN-118834244-A | N-heterocyclic carbene-Schiff base type Csp2^Nsp2Bidentate ring palladium complex and synthetic method and application thereof | 常州大学 | 2024-10-25 | — | — | CN | claimed |
| CN-118666659-A | Benzoin based on benzimidazole bromide catalysis and synthesis method of benzoin derivative | 合肥大学 | 2024-09-20 | — | — | CN | claimed |
| CN-116675609-A | Strong alkaline ionic liquid and preparation method and application thereof | 沈阳化工大学 | 2023-09-01 | — | — | CN | claimed |
| CN-111635437-B | Palladium complex containing ortho-carborane benzimidazole structure, and preparation method and application thereof | 上海应用技术大学 | 2023-04-28 | — | — | CN | claimed |
| US-20230123029-A1 | ZIF NANOPARTICLE CONTAINING TRI-LIGANDS, THE METHOD OF MANUFACTURING THE SAME, MIXED MATRIX MEMBRANE COMPRISING THE SAME AND METHOD OF SEPARATING GAS USING THE MEMBRANE | SOGANG UNIVERSITY RESEARCH ＆ BUSINESS DEVELOPMENT FOUNDATION (KR) | 2023-04-20 | — | — | US | claimed |
| CN-110117299-B | Rhodium complex containing ortho-carbon boron alkyl benzimidazole structure and preparation and application thereof | 上海应用技术大学 | 2021-05-11 | — | — | CN | claimed |
| CN-110105403-B | Iridium complex containing carboranyl benzimidazole structure, preparation method and application thereof | 上海应用技术大学 | 2021-02-26 | — | — | CN | claimed |
| CN-110016061-B | Ruthenium complex containing carboranyl benzimidazole structure, preparation method and application thereof | 上海应用技术大学 | 2021-02-26 | — | — | CN | claimed |
| CN-111635437-A | Palladium complex containing ortho-position carborane-based benzimidazole structure and preparation method and application thereof | 上海应用技术大学 | 2020-09-08 | — | — | CN | claimed |
| CN-104892523-B | A kind of benzimidazole bromine salt compounds and its synthesis and be used as acceptor molecule bore hole colorimetric identification CN‑Application | 西北师范大学 | 2017-09-22 | — | — | CN | claimed |
| CN-105457029-A | Application of promoting expression of I-type interferon by inhibiting activity of casein kinase 2 | INST PASTEUR OF SHANGHAI CHINESE ACAD OF SCIENCES | 2016-04-06 | — | — | CN | claimed |
| CN-105315603-A | Flame-retardant thermoplastic elastomer composition | Jiaxing boer plastic co ltd | 2016-02-10 | — | — | CN | claimed |
| EP-2021330-A2 | BENZIMIDAZOLE MODULATORS OF VR1 | Janssen Pharmaceutica, N.V. (BE) | 2009-02-11 | — | — | EP | claimed |
| WO-2007130780-A2 | BENZIMIDAZOLE MODULATORS OF VR1 | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-11-15 | — | — | WO | claimed |
| US-20030027842-A1 | Halogenobenzimidazoles | ASSMANN LUTZ (DE) | 2003-02-06 | — | — | US | claimed |
| EP-0844998-A1 | HALOBENZIMIDAZOLES AND THEIR USE AS MICROBICIDES | BAYER AG (DE) | 1998-06-03 | — | — | EP | claimed |
| WO-1997006171-A1 | HALOBENZIMIDAZOLES AND THEIR USE AS MICROBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-20 | — | — | WO | claimed |
| US-4258129-A | IMPROVE GREEN SHELF LIFE | FUJI PHOTO FILM CO., LTD. (JP) | 1981-03-24 | — | — | US | claimed |
| US-4002479-A | ORGANIC SILVER SALT, SILVER HALIDE, AND A REDUCING AGENT | FUJI PHOTO FILM CO., LTD. (JA) | 1977-01-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030027842-A1 | Halogenobenzimidazoles | MSR1, MRPS23, CBR1 | TDP1 3173/4885HTT 4289/4885SMN1; SMN2 4773/4885 |
| US-20230123029-A1 | ZIF NANOPARTICLE CONTAINING TRI-LIGANDS, THE METHOD OF MANUFACTURING THE SAME, MIXED MATRIX MEMBRANE COMPRISING THE SAME AND METHOD OF SEPARATING GAS USING THE MEMBRANE | IKZF3, TIMCC, EPCAM | TDP1 4847/4885HTT 4179/4885SMN1; SMN2 4200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.