Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNG | P07510 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CHRND | Q07001 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28890241 | 0.82 | SMN1; SMN2 (0.39) | MEN1KMT2ASMN1; SMN2KDM4ETSHR | |
| SCHEMBL22039758 | 0.77 | TRPA1 (0.42) | ALDH1A1SMN1; SMN2KDM4ETSHRLMNA | |
| SCHEMBL22039739 | 0.77 | TRPA1 (0.42) | ALDH1A1SMN1; SMN2KDM4ETSHRLMNA | |
| SCHEMBL31149152 | 0.77 | TRPA1 (0.42) | ALDH1A1SMN1; SMN2KDM4ETSHRLMNA | |
| SCHEMBL30471005 | 0.76 | LMNA (0.40) | MEN1KMT2ASMN1; SMN2KDM4ETSHR | |
| SCHEMBL24365220 | 0.76 | LMNA (0.40) | MEN1KMT2ASMN1; SMN2KDM4ETSHR | |
| SCHEMBL23891810 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2KDM4ETSHRLMNATAS1R3 | |
| SCHEMBL20835832 | 0.73 | PPARA (0.52) | ALDH1A1KDM4EMAPT | |
| SCHEMBL20835831 | 0.73 | PPARA (0.52) | ALDH1A1KDM4EMAPT | |
| SCHEMBL23878297 | 0.73 | CFTR (0.37) | HTTALDH1A1KDM4EMAPTTAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889138-B1 | HISTONE ACETYLASE P300 INHIBITOR AND USE THEREOF | HINOVA PHARMACEUTICALS INC (CN) | 2024-11-20 | — | — | EP | disclosed |
| CN-111217802-B | Histone acetylase p300 inhibitor and application thereof | 海创药业股份有限公司 | 2021-10-08 | — | — | CN | disclosed |
| EP-3889138-A1 | HISTONE ACETYLASE P300 INHIBITOR AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2021-10-06 | — | — | EP | disclosed |
| CN-111217802-A | Histone acetylase p300 inhibitor and application thereof | 成都海创药业有限公司 | 2020-06-02 | — | — | CN | disclosed |