SCHEMBL23879568

SCHEMBL23879568

C=C(CCNC(=O)c1ccc(C(F)(F)F)cc1NS(=O)(=O)c1ccc(S(=O)(=O)C(F)F)cc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 4/20 0.47
▸ USP8 P40818 4/20 0.47
▸ ACLY P53396 3/20 0.46
▸ USP36 Q9P275 1/20 0.46
▸ KDM1A O60341 2/20 0.46
▸ KCNA5 P22460 1/20 0.44
▸ MAPT P10636 1/20 0.43
▸ GPR27 Q9NS67 4/20 0.42
▸ AVPR2 P30518 3/20 0.42
▸ LMNA P02545 1/20 0.41
▸ CCR1 P32246 1/20 0.41
▸ CCR2 P41597 1/20 0.41
▸ NPC1 O15118 1/20 0.41
▸ RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24268135 0.89 USP2 (0.47) USP2USP8ACLYUSP36KDM1A
SCHEMBL23879544 0.88 KDM1A (0.49) USP2USP8ACLYUSP36KDM1A
SCHEMBL23879578 0.87 USP2 (0.46) USP2USP8ACLYUSP36KDM1A
SCHEMBL23879622 0.87 USP2 (0.46) USP2USP8ACLYUSP36KDM1A
SCHEMBL23879530 0.83 ACLY (0.52) USP2USP8ACLYUSP36KDM1A
SCHEMBL23879624 0.83 USP2 (0.44) USP2USP8ACLYUSP36KDM1A
SCHEMBL23879531 0.83 MCL1 (0.40) USP2USP8ACLYUSP36KCNA5
SCHEMBL23879648 0.81 USP2 (0.42) USP2USP8ACLYUSP36KDM1A
SCHEMBL24268039 0.81 RAB9A (0.43) USP2USP8ACLYUSP36LMNA
SCHEMBL23879626 0.79 USP2 (0.48) USP2USP8ACLYUSP36KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220055985-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES GILEAD SCIENCES, INC. 2022-02-24 — — US disclosed
US-11136290-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives THE LIVER COMPANY INC. (US) 2021-10-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220055985-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES STS, SULT2A1, SCN2B USP2 3178/4885USP8 3142/4885ACLY 2228/4885
US-11136290-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives STS, SULT2A1, SCN2B USP2 3178/4885USP8 3142/4885ACLY 2228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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