Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MME | P08473 | 1/20 | 0.53 |
| ▸ | ECE1 | P42892 | 1/20 | 0.53 |
| ▸ | CETP | P11597 | 3/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 10/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.49 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.48 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23881985 | 0.89 | ACE2 (0.53) | MMEECE1 | |
| SCHEMBL23881979 | 0.88 | ACE2 (0.53) | MMEECE1 | |
| SCHEMBL28666960 | 0.87 | MME (0.51) | MMEECE1CETPSIRT2SIRT1 | |
| SCHEMBL23881969 | 0.86 | ACE2 (0.55) | MMEECE1 | |
| SCHEMBL23881665 | 0.85 | ECE1 (0.50) | MMEECE1 | |
| SCHEMBL28674530 | 0.84 | ECE1 (0.46) | MMEECE1 | |
| SCHEMBL23881683 | 0.84 | MMP8 (0.52) | MMEECE1 | |
| SCHEMBL23881893 | 0.84 | ACE2 (0.48) | MMEECE1SIRT2SIRT1 | |
| SCHEMBL23881738 | 0.83 | CASP1 (0.51) | MMEECE1 | |
| SCHEMBL11163834 | 0.83 | MME (0.55) | MMEECE1CETPSIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210309677-A1 | NOVEL AMINOPHOSPHINIC DERIVATIVES AS AMINOPEPTIDASE A INHIBITORS | COLLEGE DE FRANCE (FR) | 2021-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210309677-A1 | NOVEL AMINOPHOSPHINIC DERIVATIVES AS AMINOPEPTIDASE A INHIBITORS | ANPEP, DNPEP, ENPEP | MEN1 1356/4885ALDH1A1 2988/4885HPGD 1843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.