Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | LAP3 | P28838 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23883244 | 1.00 | CTSK (0.43) | CTSKALDH1A1FOLH1MEN1LMNA | |
| SCHEMBL25526555 | 0.91 | POLB (0.47) | CTSKFOLH1CTSSCTSLCNR2 | |
| SCHEMBL25528013 | 0.91 | POLB (0.47) | CTSKFOLH1CTSSCTSLCNR2 | |
| SCHEMBL28951151 | 0.91 | POLB (0.47) | CTSKFOLH1CTSSCTSLCNR2 | |
| SCHEMBL23883369 | 0.86 | ALDH1A1 (0.45) | CTSKALDH1A1FOLH1MEN1LMNA | |
| SCHEMBL23883367 | 0.86 | ALDH1A1 (0.45) | CTSKALDH1A1FOLH1MEN1LMNA | |
| SCHEMBL7340018 | 0.85 | CTSK (0.56) | CTSKALDH1A1FOLH1MEN1LMNA | |
| SCHEMBL7340009 | 0.85 | CTSK (0.56) | CTSKALDH1A1FOLH1MEN1LMNA | |
| SCHEMBL24113428 | 0.82 | CTSK (0.48) | CTSKCTSSCTSL | |
| SCHEMBL23836198 | 0.82 | NAAA (0.37) | CTSKLMNACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667215-B | Broad-spectrum antiviral medicine for resisting coronavirus | 堪萨斯州立大学研究基金会 | 2026-05-19 | — | — | CN | disclosed |
| US-12583820-B2 | Broad spectrum antivirals against coronavirus | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2026-03-24 | — | — | US | disclosed |
| US-20230159453-A1 | INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION | COCRYSTAL PHARMA, INC. | 2023-05-25 | — | — | US | disclosed |
| US-20230159453-A1 | INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION | COCRYSTAL PHARMA, INC. | 2023-05-25 | — | — | US | disclosed |
| US-20230150933-A1 | BROAD SPECTRUM ANTIVIRALS AGAINST CORONAVIRUS | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2023-05-18 | — | — | US | disclosed |
| EP-4132944-A1 | INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION | Cocrystal Pharma, Inc. (US) | 2023-02-15 | — | — | EP | disclosed |
| EP-4126816-A1 | BROAD SPECTRUM ANTIVIRALS AGAINST CORONAVIRUS | Kansas State University Research Foundation (US) | 2023-02-08 | — | — | EP | disclosed |
| CN-115698035-A | Inhibitors of norovirus and coronavirus replication | 共晶制药公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-115667215-A | Broad-spectrum antiviral medicine for resisting coronavirus | 堪萨斯州立大学研究基金会 | 2023-01-31 | — | — | CN | disclosed |
| WO-2021202460-A1 | BROAD SPECTRUM ANTIVIRALS AGAINST CORONAVIRUS | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2021-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12583820-B2 | Broad spectrum antivirals against coronavirus | SARS1, NSUN2, ZC3HAV1 | CTSK 2825/4885ALDH1A1 1431/4885FOLH1 3080/4885 |
| US-20230159453-A1 | INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION | VIM, ACE, ACE2 | CTSK 2355/4885ALDH1A1 1895/4885FOLH1 3544/4885 |
| US-20230150933-A1 | BROAD SPECTRUM ANTIVIRALS AGAINST CORONAVIRUS | SARS1, ZC3HAV1, POLL | CTSK 1900/4885ALDH1A1 2499/4885FOLH1 2986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.