Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCND3 | P30281 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 3/20 | 0.39 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2390633 | 0.84 | CDK2 (0.47) | MAPK1CCNA2CDK2PIM1CDK4 | |
| SCHEMBL2390628 | 0.79 | CSNK2A1 (0.57) | MAPK1CCNA2CDK2CDK4MTOR | |
| SCHEMBL2387410 | 0.75 | CAMK2D (0.52) | MAPK1CCNA2CDK2CDK4MTOR | |
| SCHEMBL27843897 | 0.72 | DYRK1A (0.49) | MAPK1CCNA2CDK2PIM1CDK4 | |
| SCHEMBL2330123 | 0.71 | PLK1 (0.56) | MAPK1CCNA2CDK2PIM1CDK4 | |
| SCHEMBL4892481 | 0.69 | CAMK2D (0.53) | MAPK1CCNA2CDK2PIM1CDK4 | |
| SCHEMBL2403389 | 0.69 | CAMK2D (0.52) | MAPK1CCNA2CDK2PIM1CDK4 | |
| SCHEMBL2333324 | 0.68 | CDK2 (0.53) | MAPK1CCNA2CDK2PIM1CDK4 | |
| SCHEMBL3647915 | 0.68 | DKK1 (0.48) | MAPK1GSK3BMAPK8MAPTCAMK2D | |
| SCHEMBL38657570 | 0.67 | IDO1 (0.51) | CCNA2CDK2PIM1CDK4CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2205086-B1 | FUNGICIDAL HETEROCYCLIC AMINES | DU PONT (US) | 2013-08-14 | — | — | EP | disclosed |
| US-20110301123-A1 | Fungicidal Heterocyclic Amines | E.I. DU PONT NEMOURS AND COMPANY (US) | 2011-12-08 | — | — | US | disclosed |
| US-8026359-B2 | Fungicidal heterocyclic amines | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-09-27 | — | — | US | disclosed |
| US-20100267729-A1 | FUNGICIDAL HETEROCYCLIC AMINES | E.I. DU PONT DE NEMOURS AND COMPANY (DE) | 2010-10-21 | — | — | US | disclosed |
| EP-2205086-A2 | FUNGICIDAL HETEROCYCLIC AMINES | E. I. du Pont de Nemours and Company (US) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009061761-A2 | FUNGICIDAL HETEROCYCLIC AMINES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267729-A1 | FUNGICIDAL HETEROCYCLIC AMINES | PRMT9, MAOB, CYP2C9 | MAPK1 1947/4885CCNA2 920/4885CDK2 2324/4885 |
| US-20110301123-A1 | Fungicidal Heterocyclic Amines | PRMT9, MAOB, CYP2C9 | MAPK1 1947/4885CCNA2 920/4885CDK2 2324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.