Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.40 |
| ▸ | KDM6B | O15054 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ASPH | Q12797 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26318975 | 0.86 | ALDH1A1 (0.44) | ALDH1A1KDM4EKDM4CKDM6BKMT2A | |
| SCHEMBL26169923 | 0.81 | KDM4E (0.41) | ALDH1A1KDM4EPOLBNR3C2 | |
| SCHEMBL23900661 | 0.80 | CA12 (0.41) | ALDH1A1KDM4EPOLBHPGDL3MBTL1 | |
| SCHEMBL12285807 | 0.79 | KDM5A (0.43) | ALDH1A1KDM4EKDM4CNR3C2KDM5A | |
| SCHEMBL2621649 | 0.79 | KDM5A (0.43) | ALDH1A1KDM4EKDM4CNR3C2KDM5A | |
| SCHEMBL2621648 | 0.79 | KDM5A (0.43) | ALDH1A1KDM4EKDM4CNR3C2KDM5A | |
| SCHEMBL262347 | 0.76 | ALDH1A1 (0.50) | ALDH1A1KDM4EPOLBNR3C2HPGD | |
| SCHEMBL783184 | 0.76 | KDM4C (0.42) | ALDH1A1KDM4EKDM4CKDM6BKMT2A | |
| SCHEMBL24707476 | 0.73 | ALDH1A1 (0.43) | ALDH1A1KDM4EPOLBNR3C2L3MBTL1 | |
| SCHEMBL2621556 | 0.72 | ALDH1A1 (0.38) | ALDH1A1POLBNR3C2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250361223-A1 | AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LTD (CN) | 2025-11-27 | — | — | US | disclosed |
| US-12435062-B2 | Amide compounds and uses thereof | HUTCHISON MEDIPHARMA LIMITED (CN) | 2025-10-07 | — | — | US | disclosed |
| CN-117777103-A | Amide compound and application thereof | 和记黄埔医药（上海）有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117720520-A | Amide compound and application thereof | 和记黄埔医药（上海）有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-117720519-A | Amide compound and application thereof | 和记黄埔医药（上海）有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-115315422-B | Amide compound and application thereof | 和记黄埔医药（上海）有限公司 | 2023-11-07 | — | — | CN | disclosed |
| US-20230174513-A1 | AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2023-06-08 | — | — | US | disclosed |
| US-20230174513-A1 | AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2023-06-08 | — | — | US | disclosed |
| US-20230174513-A1 | AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2023-06-08 | — | — | US | disclosed |
| EP-4126844-A1 | AMIDE COMPOUNDS AND USES THEREOF | Hutchison Medipharma Limited (CN) | 2023-02-08 | — | — | EP | disclosed |
| CN-115315422-A | Amide compound and application thereof | 和记黄埔医药（上海）有限公司 | 2022-11-08 | — | — | CN | disclosed |
| WO-2021197276-A1 | Amide compounds and uses thereof | HUTCHISON MEDIPHARMA LIMITED (CN) | 2021-10-07 | — | — | WO | disclosed |
| WO-2021197276-A1 | Amide compounds and uses thereof | HUTCHISON MEDIPHARMA LIMITED (CN) | 2021-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174513-A1 | AMIDE COMPOUNDS AND USES THEREOF | ASNS, ASS1, NAT1 | ALDH1A1 610/4885KDM4E 1449/4885KDM4C 1516/4885 |
| US-12435062-B2 | Amide compounds and uses thereof | ASNS, ASS1, NAT1 | ALDH1A1 610/4885KDM4E 1449/4885KDM4C 1516/4885 |
| US-20250361223-A1 | AMIDE COMPOUNDS AND USES THEREOF | ASNS, NAT1, AADAC | ALDH1A1 585/4885KDM4E 1690/4885KDM4C 1951/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.