Sugi Predict

Sugi Predict / Compounds / SCHEMBL262347

SCHEMBL262347

SCHEMBL262347

CC(C)n1nccc1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.50
▸ GAA P10253 1/20 0.45
▸ KDM4E B2RXH2 1/20 0.40
▸ NR3C2 P08235 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ HCAR3 P49019 1/20 0.39
▸ HCAR2 Q8TDS4 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ TDP1 Q9NUW8 1/20 0.37
▸ CCNC P24863 1/20 0.35
▸ CDK8 P49336 1/20 0.35
▸ HASPIN Q8TF76 1/20 0.35
▸ HTT P42858 1/20 0.35
▸ POLB P06746 1/20 0.34
▸ PIK3CD O00329 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25530100 0.84 ALDH1A1 (0.46) ALDH1A1GAAKDM4ENR3C2HPGD
SCHEMBL28604816 0.83 ALDH1A1 (0.46) ALDH1A1GAANR3C2L3MBTL1TDP1
SCHEMBL22143745 0.83 ALDH1A1 (0.46) ALDH1A1GAANR3C2L3MBTL1TDP1
SCHEMBL22143744 0.83 ALDH1A1 (0.46) ALDH1A1GAANR3C2L3MBTL1TDP1
SCHEMBL24593529 0.83 ALDH1A1 (0.42) ALDH1A1GAAKDM4EL3MBTL1TDP1
SCHEMBL1118900 0.82 ALDH1A1 (0.44) ALDH1A1GAAKDM4ENR3C2L3MBTL1
SCHEMBL2307447 0.82 NR3C2 (0.48) ALDH1A1GAAKDM4ENR3C2L3MBTL1
SCHEMBL9813557 0.82 ALDH1A1 (0.44) ALDH1A1GAAKDM4ENR3C2L3MBTL1
SCHEMBL22143921 0.82 ALDH1A1 (0.45) ALDH1A1GAAHCAR3L3MBTL1TDP1
SCHEMBL22143750 0.82 L3MBTL1 (0.54) ALDH1A1GAAKDM4EHPGDHCAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1902025-A1 KINASE INHIBITORS Allergan, Inc. (US) 2008-03-26 — — EP claimed
US-20070032478-A1 Kinase Inhibitors ALLERGAN, INC. 2007-02-08 — — US claimed
WO-2007008895-A1 KINASE INHIBITORS ALLERGAN, INC. (US) 2007-01-18 — — WO claimed
US-12637430-B2 Interleukin-17 (IL-17) inhibitors HITGEN INC. (CN) 2026-05-26 — — US disclosed
EP-4143193-B1 IMIDAZOPYRIMIDINES AS MODULATORS OF IL-17 JANSSEN PHARMACEUTICA NV (BE) 2026-04-22 — — EP disclosed
US-12600728-B2 Interleukin-17 inhibitors NOVARTIS AG (CH) 2026-04-14 — — US disclosed
US-20260083708-A1 IL-17 MODULATORS AND USES THEREOF NNOCARE PHARMA INC (US) 2026-03-26 — — US disclosed
EP-4713318-A2 SMALL MOLECULE MODULATORS OF IL-17A, METHODS OF MAKING AND METHODS OF USING THEREOF ASCLETIS PHARMA (CHINA) CO., LIMITED (HK) 2026-03-25 — — EP disclosed
EP-4711365-A1 THIAZOLE DERIVATIVE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF Shanghai Hansoh Biomedical Co., Ltd. (CN) 2026-03-18 — — EP disclosed
US-12570675-B2 Boronic acid compounds LG CHEM, LTD. (KR) 2026-03-10 — — US disclosed
US-12559496-B2 Imidazopyrimidines as modulators of IL-17 JANSSEN PHARMACEUTICA NV (BE) 2026-02-24 — — US disclosed
EP-2155727-A1 N-[6-AMINO-5-(PHENYL)PYRAZIN-2-YL]-ISOXAZOLE-4-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS NAV1.8 CHANNEL MODULATORS FOR THE TREATMENT OF PAIN Pfizer Limited (GB) 2010-02-24 — — EP disclosed
WO-2009147188-A1 BENZPYRAZOL DERIVATIVES AS INHIBITORS OF PI3 KINASES GLAXO GROUP LIMITED (GB) 2009-12-10 — — WO disclosed
US-20090208557-A1 Kinase inhibitors ALLERGAN, INC. 2009-08-20 — — US disclosed
US-20090048306-A1 PYRIDINE DERIVATIVES PFIZER, INC. (US) 2009-02-19 — — US disclosed
WO-2008135830-A1 N- [6-AMINO-S- (PHENYL) PYRAZIN-2-YL] -ISOXAZOLE-4-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS NAV1.8 CHANNEL MODULATORS FOR THE TREATMENT OF PAIN PFIZER LIMITED (GB) 2008-11-13 — — WO disclosed
WO-2008135826-A2 2 -PYRIDINE CARBOXAMIDE DERIVATIVES AS SODIUM CHANNEL MODULATORS PFIZER LIMITED (GB) 2008-11-13 — — WO disclosed
EP-1902025-A1 KINASE INHIBITORS Allergan, Inc. (US) 2008-03-26 — — EP disclosed
US-20070032478-A1 Kinase Inhibitors ALLERGAN, INC. 2007-02-08 — — US disclosed
WO-2007008895-A1 KINASE INHIBITORS ALLERGAN, INC. (US) 2007-01-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637430-B2 Interleukin-17 (IL-17) inhibitors IL17A, IL2, IL23R ALDH1A1 335/4885GAA 4577/4885KDM4E 3282/4885
US-12570675-B2 Boronic acid compounds PSMB6, PSMB3, PSMB2 ALDH1A1 3621/4885GAA 605/4885KDM4E 3458/4885
US-20090208557-A1 Kinase inhibitors PTK2, MAP3K6, MAP3K20 ALDH1A1 2605/4885GAA 1736/4885KDM4E 891/4885
US-20260083708-A1 IL-17 MODULATORS AND USES THEREOF IL17A, IL2, IL23R ALDH1A1 1481/4885GAA 4603/4885KDM4E 3125/4885
US-20090048306-A1 PYRIDINE DERIVATIVES SDHA, P2RX4, P2RX3 ALDH1A1 192/4885GAA 1652/4885KDM4E 2630/4885
US-12559496-B2 Imidazopyrimidines as modulators of IL-17 IL17A, IL2, IL23R ALDH1A1 145/4885GAA 3492/4885KDM4E 2817/4885
US-20070032478-A1 Kinase Inhibitors ABL1, LCK, ERBB2 ALDH1A1 2379/4885GAA 1455/4885KDM4E 1393/4885
US-12600728-B2 Interleukin-17 inhibitors IL17A, IL2, IL1B ALDH1A1 958/4885GAA 4682/4885KDM4E 2847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.