Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29421618 | 0.79 | PDPK1 (0.44) | DYRK1ARENDCPSDHFR | |
| SCHEMBL17223741 | 0.79 | PDPK1 (0.44) | DYRK1ARENDCPSDHFR | |
| SCHEMBL4872319 | 0.76 | DYRK1A (0.33) | DYRK1ARIPK1RENDCPSMAPK1 | |
| SCHEMBL4106056 | 0.76 | DYRK1A (0.50) | DYRK1ATNFRIPK1 | |
| SCHEMBL18194317 | 0.72 | CHUK (0.40) | RENDHFR | |
| SCHEMBL21727172 | 0.72 | DYRK1A (0.31) | DYRK1AREN | |
| SCHEMBL20274839 | 0.72 | REN (0.41) | DYRK1ARENDCPSMAPK1DHFR | |
| SCHEMBL27964697 | 0.67 | REN (0.41) | RENDHFR | |
| SCHEMBL31745118 | 0.64 | PIK3CA (0.31) | DYRK1ATNFRIPK1MAPK1PIK3CA | |
| SCHEMBL4838531 | 0.64 | DYRK1A (0.41) | DYRK1ATNFRIPK1MAPK1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889152-A1 | HETEROAROMATIC DERIVATIVES FOR USE AS REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | Jiangsu Hansoh Pharmaceutical Group Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |