Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20674123 | 0.79 | HTT (0.47) | HTTPTK2MAPTSLC2A1 | |
| SCHEMBL19661001 | 0.76 | HTT (0.44) | HTTPTK2MAPTSLC2A1 | |
| SCHEMBL8423993 | 0.74 | HTT (0.42) | HTTPTK2MAPTSLC2A1 | |
| SCHEMBL22268064 | 0.73 | HTT (0.41) | HTTPTK2MAPTSLC2A1 | |
| SCHEMBL19964519 | 0.67 | HTT (0.52) | HTTPTK2MAPTSLC2A1 | |
| SCHEMBL20272422 | 0.65 | SLC2A1 (0.47) | HTTPTK2MAPTSLC2A1 | |
| SCHEMBL21958684 | 0.64 | HTT (0.44) | HTTPTK2MAPTSLC2A1 | |
| SCHEMBL6850410 | 0.63 | HTT (0.47) | HTTPTK2MAPTSLC2A1 | |
| SCHEMBL4141412 | 0.63 | CDC7 (0.47) | HTTPTK2MAPT | |
| SCHEMBL10803369 | 0.63 | SLC2A1 (0.44) | HTTPTK2MAPTSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889152-A1 | HETEROAROMATIC DERIVATIVES FOR USE AS REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | Jiangsu Hansoh Pharmaceutical Group Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |