Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23890863 | 0.70 | KDM4E (0.56) | KDM4EAPOBEC3AAPOBEC3GALDH1A1LMNA | |
| SCHEMBL23890840 | 0.63 | KDM4E (0.40) | KDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL24099873 | 0.63 | NPSR1 (0.41) | KDM4EAPOBEC3AAPOBEC3GRAB9A | |
| SCHEMBL12254884 | 0.62 | NPSR1 (0.42) | MTNR1AMTNR1BKDM4ETP53HSD17B10 | |
| SCHEMBL27811038 | 0.62 | MTNR1A (0.47) | MTNR1AMTNR1BHSD17B10SMN1; SMN2NPC1 | |
| SCHEMBL8851377 | 0.61 | — | — | |
| SCHEMBL800814 | 0.60 | — | — | |
| SCHEMBL8924401 | 0.60 | KMT2A (0.67) | MTNR1AMTNR1BKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL27402376 | 0.59 | KDM4E (0.46) | KDM4EAPOBEC3AAPOBEC3GHSD17B10SMN1; SMN2 | |
| SCHEMBL18478347 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889154-A1 | HETEROCYCLIC COMPOUND INTERMEDIATE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Wuhan LL Science And Technology Development Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |