SCHEMBL23890840

SCHEMBL23890840

Cc1ccn(C(C)OCCO)c(=N)c1

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.40
APOBEC3A P31941 1/20 0.40
APOBEC3G Q9HC16 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23890863 0.74 KDM4E (0.56) KDM4EAPOBEC3AAPOBEC3G
SCHEMBL14389711 0.67 PKM (0.43)
SCHEMBL11102286 0.67 PKM (0.43)
SCHEMBL10883376 0.66 MAPT (0.33) KDM4E
SCHEMBL14816681 0.65 FGFR1 (0.41)
SCHEMBL12658010 0.65 FGFR1 (0.41)
SCHEMBL23890771 0.63 MTNR1A (0.40) KDM4EAPOBEC3AAPOBEC3G
SCHEMBL10474801 0.60 SMN1; SMN2 (0.52)
SCHEMBL21859350 0.58
SCHEMBL23890597 0.58 KDM4E (0.54) KDM4EAPOBEC3AAPOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3889154-A1 HETEROCYCLIC COMPOUND INTERMEDIATE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Wuhan LL Science And Technology Development Co., Ltd. (CN) 2021-10-06 EP disclosed