SCHEMBL2389083

SCHEMBL2389083

CCc1sc2cccc(C)c2c1CC

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.34
CNR1 P21554 1/20 0.34
ALDH1A1 P00352 3/20 0.33
MAPT P10636 1/20 0.31
GAA P10253 2/20 0.31
KDM4E B2RXH2 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
GLA P06280 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MAPK1 P28482 1/20 0.31
ADRA2A P08913 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
ADRA1D P25100 1/20 0.31
ADRA1A P35348 1/20 0.31
ADRA1B P35368 1/20 0.31
ATM Q13315 1/20 0.30
PLAU P00749 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2388153 0.88 CNR2 (0.36) CNR2CNR1ALDH1A1KDM4ETSHR
SCHEMBL2387092 0.83 CNR2 (0.35) CNR2CNR1ALDH1A1MAPTGAA
SCHEMBL2389044 0.78 ADRA2A (0.33) GAAADRA2AADRA2BADRA2CADRA1D
SCHEMBL2388008 0.73 CNR2 (0.38) CNR2CNR1ALDH1A1GAAKDM4E
SCHEMBL4160530 0.73 ALDH1A1 (0.43) ALDH1A1MAPTGAATSHRATM
SCHEMBL14045624 0.71 CNR2 (0.46) CNR2CNR1ALDH1A1KDM4EL3MBTL1
SCHEMBL2387338 0.70
SCHEMBL13193913 0.68 ALDH1A1 (0.32) ALDH1A1GAAKDM4EL3MBTL1GLA
SCHEMBL22826514 0.68 ALDH1A1 (0.45) CNR2CNR1ALDH1A1GAAKDM4E
SCHEMBL597056 0.67 CYP2A6 (0.45) ALDH1A1MAPTTSHRATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9969943-B2 Use of magnetic nanoparticles for depletion of aromatic compounds in oil MAERSK OLIE OG GAS A/S (DK) 2018-05-15 US disclosed
US-20160272898-A1 USE OF MAGNETIC NANOPARTICLES FOR DEPLETION OF AROMATIC COMPOUNDS IN OIL TOTAL E&P DANMARK A/S (DK) 2016-09-22 US disclosed
WO-2015044449-A1 USE OF MAGNETIC NANOPARTICLES FOR DEPLETION OF AROMATIC COMPOUNDS IN OIL MÆRSK OLIE OG GAS A/S (DK) 2015-04-02 WO disclosed
US-8021540-B2 Method of desulfurizing hydrocarbon oil JAPAN ENERGY CORPORATION (JP) 2011-09-20 US disclosed
US-20100227229-A1 SOLID ACID, METHOD FOR PREPARING THE SOLID ACID, AND METHOD FOR DESULFURIZING HYDROCARBON OIL USING THE SOILD ACID AS DESULFURIZING AGENT JAPAN ENERGY CORPORATION (JP) 2010-09-09 US disclosed
EP-2202204-A1 SOLID ACID, PROCESS FOR PRODUCING THE SOLID ACID, METHOD FOR DESULFURIZING HYDROCARBON OIL USING SOLID ACID AS DESULFURIZING AGENT Japan Energy Corporation (JP) 2010-06-30 EP disclosed
US-20100155303-A1 METHOD FOR DESULFURIZATION OF HYDROCARBON OIL JAPAN ENERGY CORPORATION (JP) 2010-06-24 US disclosed
US-20090000990-A1 Method of Desulfurizing Hydrocarbon Oil JAPAN ENERGY CORPORATION (JP) 2009-01-01 US disclosed
EP-1923451-A1 METHOD FOR DESULFURIZATION OF HYDROCARBON OIL JAPAN ENERGY CORPORATION (JP) 2008-05-21 EP disclosed
EP-1715025-A1 METHOD OF DESULFURIZING HYDROCARBON OIL JAPAN ENERGY CORPORATION (JP) 2006-10-25 EP disclosed