SCHEMBL2389044

SCHEMBL2389044

CCc1sc2ccc(C)c(C)c2c1CC

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
ADRA1D P25100 1/20 0.33
ADRA1A P35348 1/20 0.33
ADRA1B P35368 1/20 0.33
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2386580 0.88 KDM4E (0.35)
SCHEMBL2387730 0.85 ADRA2A (0.35) ADRA2AADRA2BADRA2CADRA1DADRA1A
SCHEMBL2387338 0.78
SCHEMBL2389083 0.78 CNR2 (0.34) ADRA2AADRA2BADRA2CADRA1DADRA1A
SCHEMBL2388304 0.74 GAA (0.32) GAA
SCHEMBL2387092 0.68 CNR2 (0.35) ADRA2AADRA2BADRA2CADRA1DADRA1A
SCHEMBL25456391 0.68 GABRA1 (0.35) GAA
SCHEMBL2384277 0.67 ALDH1A1 (0.33)
SCHEMBL2388153 0.67 CNR2 (0.36)
SCHEMBL2386571 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9969943-B2 Use of magnetic nanoparticles for depletion of aromatic compounds in oil MAERSK OLIE OG GAS A/S (DK) 2018-05-15 US disclosed
US-20160272898-A1 USE OF MAGNETIC NANOPARTICLES FOR DEPLETION OF AROMATIC COMPOUNDS IN OIL TOTAL E&P DANMARK A/S (DK) 2016-09-22 US disclosed
WO-2015044449-A1 USE OF MAGNETIC NANOPARTICLES FOR DEPLETION OF AROMATIC COMPOUNDS IN OIL MÆRSK OLIE OG GAS A/S (DK) 2015-04-02 WO disclosed
US-8021540-B2 Method of desulfurizing hydrocarbon oil JAPAN ENERGY CORPORATION (JP) 2011-09-20 US disclosed
US-20100227229-A1 SOLID ACID, METHOD FOR PREPARING THE SOLID ACID, AND METHOD FOR DESULFURIZING HYDROCARBON OIL USING THE SOILD ACID AS DESULFURIZING AGENT JAPAN ENERGY CORPORATION (JP) 2010-09-09 US disclosed
EP-2202204-A1 SOLID ACID, PROCESS FOR PRODUCING THE SOLID ACID, METHOD FOR DESULFURIZING HYDROCARBON OIL USING SOLID ACID AS DESULFURIZING AGENT Japan Energy Corporation (JP) 2010-06-30 EP disclosed
US-20100155303-A1 METHOD FOR DESULFURIZATION OF HYDROCARBON OIL JAPAN ENERGY CORPORATION (JP) 2010-06-24 US disclosed
US-20090000990-A1 Method of Desulfurizing Hydrocarbon Oil JAPAN ENERGY CORPORATION (JP) 2009-01-01 US disclosed
EP-1923451-A1 METHOD FOR DESULFURIZATION OF HYDROCARBON OIL JAPAN ENERGY CORPORATION (JP) 2008-05-21 EP disclosed
EP-1715025-A1 METHOD OF DESULFURIZING HYDROCARBON OIL JAPAN ENERGY CORPORATION (JP) 2006-10-25 EP disclosed