Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16795842 | 0.76 | MAOA (0.48) | MAOAMAOBTSHRSMN1; SMN2TAS1R3 | |
| SCHEMBL17411439 | 0.76 | MAOA (0.48) | MAOAMAOBTSHRSMN1; SMN2TAS1R3 | |
| SCHEMBL27758033 | 0.76 | MAOA (0.48) | MAOAMAOBTSHRSMN1; SMN2TAS1R3 | |
| SCHEMBL23891634 | 0.76 | MAOA (0.47) | MAOAMAOBSMN1; SMN2HPGD | |
| SCHEMBL25555258 | 0.76 | HTT (0.50) | SMN1; SMN2LMNATAS1R3TAS1R1MEN1 | |
| SCHEMBL23891544 | 0.74 | CES2 (0.43) | MAOAMAOB | |
| SCHEMBL23891540 | 0.73 | CES2 (0.35) | — | |
| SCHEMBL7982038 | 0.72 | MAOA (0.43) | MAOAMAOBTSHRKDM4ESMN1; SMN2 | |
| SCHEMBL8252464 | 0.70 | KCNQ3 (0.44) | MAOAMAOBTSHRSMN1; SMN2TAS1R3 | |
| SCHEMBL19750356 | 0.70 | TSHR (0.46) | MAOAMAOBTSHRKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889138-A1 | HISTONE ACETYLASE P300 INHIBITOR AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2021-10-06 | — | — | EP | disclosed |