Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8296527 | 0.83 | KCNQ3 (0.41) | MAOBKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL15517335 | 0.83 | TAS1R3 (0.43) | MAOAMAOBTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8252464 | 0.81 | KCNQ3 (0.44) | MAOAMAOBTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL16956565 | 0.81 | TAS1R3 (0.45) | MAOAMAOBTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL2014424 | 0.80 | TSHR (0.52) | MAPTMEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL6963321 | 0.80 | CES2 (0.54) | MAOAMAOBTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL31599679 | 0.80 | TSHR (0.52) | MAPTMEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL16955007 | 0.80 | TAS1R3 (0.39) | MAOAMAOBTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL18405331 | 0.79 | TAS1R3 (0.41) | MAOAMAOBTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL75563 | 0.79 | MEN1 (0.51) | MAOAMAOBTAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140101-A2 | IMIDAZOPYRIDINE COMPOUNDS USEFUL AS MMP-13 INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-19 | — | — | WO | disclosed |