Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23891578 | 0.86 | CYP3A4 (0.35) | CYP3A4CYP1A2POLBCYP2C19KDM4E | |
| SCHEMBL23891650 | 0.86 | CYP3A4 (0.35) | CYP3A4CYP1A2POLBCYP2C19KDM4E | |
| SCHEMBL22040145 | 0.69 | BACE1 (0.35) | — | |
| SCHEMBL23891742 | 0.68 | TSHR (0.34) | CYP3A4POLBCREBBP | |
| SCHEMBL23891526 | 0.62 | ALDH1A1 (0.43) | CYP3A4ALDH1A1 | |
| SCHEMBL23891528 | 0.62 | ALDH1A1 (0.43) | CYP3A4ALDH1A1 | |
| SCHEMBL23891527 | 0.62 | ALDH1A1 (0.43) | CYP3A4ALDH1A1 | |
| SCHEMBL12810958 | 0.59 | MMP12 (0.47) | CYP3A4CYP1A2POLBCYP2C19KDM4E | |
| SCHEMBL1911436 | 0.58 | MAPK14 (0.41) | CYP3A4CYP1A2POLBCYP2C19 | |
| SCHEMBL11225066 | 0.58 | CYP1A2 (0.51) | CYP3A4CYP1A2POLBCYP2C19MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889138-A1 | HISTONE ACETYLASE P300 INHIBITOR AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2021-10-06 | — | — | EP | disclosed |