Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812869 | 0.79 | TSHR (0.40) | ALDH1A1TSHRTDP1 | |
| SCHEMBL13354370 | 0.79 | — | — | |
| SCHEMBL19545982 | 0.79 | — | — | |
| SCHEMBL18635982 | 0.77 | TSHR (0.35) | ALDH1A1TSHRTDP1 | |
| SCHEMBL14417702 | 0.74 | TSHR (0.32) | TSHRTDP1 | |
| SCHEMBL2608664 | 0.73 | ALDH1A1 (0.32) | ALDH1A1TSHRTDP1 | |
| SCHEMBL12589081 | 0.72 | — | — | |
| SCHEMBL15911966 | 0.72 | ACACB (0.30) | — | |
| SCHEMBL24061855 | 0.70 | LMNA (0.31) | — | |
| SCHEMBL23555130 | 0.70 | LMNA (0.40) | ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3177611-B1 | OPTIONALLY FUSED HETEROCYCLYL-SUBSTITUTED DERIVATIVES OF PYRIMIDINE USEFUL FOR THE TREATMENT OF INFLAMMATORY, METABOLIC, ONCOLOGIC AND AUTOIMMUNE DISEASES | NUEVOLUTION AS (DK) | 2021-10-06 | — | — | EP | disclosed |