Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23893580 | 0.83 | KMT2A (0.37) | KMT2AKDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL23893456 | 0.83 | KDM4E (0.46) | KMT2AKDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL23893390 | 0.81 | PPARA (0.39) | KDM4ENPC1ALDH1A1RAB9APPARG | |
| SCHEMBL25898948 | 0.81 | KMT2A (0.43) | KMT2AKDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL23893507 | 0.79 | KMT2A (0.41) | KMT2AKDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL23395701 | 0.79 | ALDH1A1 (0.33) | KMT2AKDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL26291681 | 0.79 | KDM4E (0.52) | KMT2AKDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL23893418 | 0.79 | HDAC6 (0.42) | KMT2AKDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL23395704 | 0.77 | RAB9A (0.36) | KMT2AKDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL23395647 | 0.77 | NR1H2 (0.43) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889135-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | Merck Patent GmbH (DE) | 2021-10-06 | — | — | EP | disclosed |