SCHEMBL238958

SCHEMBL238958

O=[N+]([O-])c1cc([N+](=O)[O-])c(NN(c2ccccc2)c2ccccc2)c([N+](=O)[O-])c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.68
KMT2A Q03164 7/20 0.68
POLB P06746 1/20 0.68
HSP90AA1 P07900 1/20 0.52
TDP1 Q9NUW8 4/20 0.50
TSHR P16473 1/20 0.50
ALDH1A1 P00352 4/20 0.49
MAPT P10636 3/20 0.49
RAB9A P51151 3/20 0.49
LMNA P02545 2/20 0.49
NPC1 O15118 2/20 0.49
KDM4E B2RXH2 1/20 0.49
MITF O75030 1/20 0.49
ATM Q13315 2/20 0.46
CRHBP P24387 2/20 0.46
CRHR2 Q13324 2/20 0.46
TLR9 Q9NR96 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MAPK1 P28482 1/20 0.46
HTT P42858 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28099770 0.98 MEN1 (0.66) MEN1KMT2APOLBHSP90AA1TDP1
Alcohol SCHEMBL28281654 0.92 KMT2A (0.59) MEN1KMT2APOLBHSP90AA1TDP1
SCHEMBL265920 0.92 MEN1 (0.59) MEN1KMT2APOLBHSP90AA1TDP1
SCHEMBL265117 0.88 MEN1 (0.55) MEN1KMT2APOLBHSP90AA1TDP1
SCHEMBL265841 0.86 MEN1 (0.53) MEN1KMT2APOLBHSP90AA1TDP1
SCHEMBL21710428 0.86 KMT2A (0.66) MEN1KMT2APOLBHSP90AA1TDP1
SCHEMBL267113 0.85 MEN1 (0.58) MEN1KMT2APOLBHSP90AA1TDP1
SCHEMBL266152 0.85 MEN1 (0.51) MEN1KMT2APOLBHSP90AA1TDP1
SCHEMBL264956 0.83 MEN1 (0.63) MEN1KMT2APOLBTSHRALDH1A1
SCHEMBL266037 0.82 MEN1 (0.49) MEN1KMT2APOLBHSP90AA1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120089245-A Food additive formula optimization method, medium and system 青岛中信源食品科技有限公司 2025-06-03 CN claimed
CN-116199354-B Treatment method of wastewater containing 2, 5-furandicarboxylic acid 中国科学院宁波材料技术与工程研究所 2025-01-07 CN claimed
CN-119059872-A Cycloolefin monomer, cycloolefin ring-opening polymer prepared from cycloolefin monomer, preparation method and application thereof 中国石油化工股份有限公司 2024-12-03 CN claimed
CN-115598083-B Method for detecting concentration of durable free radicals of biochar 广东工业大学 2024-11-22 CN claimed
CN-115403708-B Permanent antibacterial antistatic polypropylene melt-blown material and preparation method and application thereof 杭州师范大学 2024-08-09 CN claimed
CN-116083514-B Pig bird tie-in additive and screening method thereof 青岛农业大学 2024-06-25 CN claimed
CN-117479922-A Thickening composition for thickening polar or nonpolar oils 化工产品开发公司SEPPIC 2024-01-30 CN claimed
CN-117479921-A Copolymer thickening composition for thickening polar or non-polar oils comprising at least one oil and at least one poly (itaconate) 化工产品开发公司SEPPIC 2024-01-30 CN claimed
CN-112055579-B One-component dental adhesive composition for fixing dental composite materials 3M创新有限公司 2024-01-23 CN claimed
CN-117055291-A Chemical amplification type I-line photoresist for weakening refraction influence of Al substrate and preparation and use methods thereof 徐州博康信息化学品有限公司 2023-11-14 CN claimed
CN-1835800-A Oxidation catalyst ASAHI CHEMICAL CORP (JP) 2006-09-20 CN claimed
US-7067691-B2 reacting an alpha-substituted acrylic acid anhydride with a 1,1-bis(trifluoromethyl)-1,3-diol to produce a 1-optionally substituted 4,4-bis(trifluoromethyl)-3-hydroxy-2-butyl ester of an optionally 2-substituted acrylic acid CENTRAL GLASS CO., LTD. (JP) 2006-06-27 US claimed
EP-1655070-A1 OXIDATION CATALYST Asahi Kasei Chemicals Corporation (JP) 2006-05-10 EP claimed
EP-1024900-A4 METHODS AND APPARATUS FOR DETERMINING ANALYTES IN VARIOUS MATRICES SAFETY ASSOCIATES INC (US) 2006-02-15 EP claimed
US-20050240052-A1 Process for producing fluorine-containing alkylsulfonylaminoethyl a-substitued acrylate CENTRAL GLASS COMPANY, LIMITED (JP) 2005-10-27 US claimed
US-20050165249-A1 Process for producing alpha-substituted acrylic acid esters CENTRAL GLASS COMPANY, LTD. (JP) 2005-07-28 US claimed
US-20040197235-A1 Methods and apparatus for determining analytes in various matrices SAFETY ASSOCIATES, INC. 2004-10-07 US claimed
US-20030064423-A1 Methods and apparatus for determining analytes in various matrices SAFETY ASSOCIATES, INC. 2003-04-03 US claimed
EP-1024900-A1 METHODS AND APPARATUS FOR DETERMINING ANALYTES IN VARIOUS MATRICES Safety Associates, Inc. (US) 2000-08-09 EP claimed
WO-1999020396-A1 METHODS AND APPARATUS FOR DETERMINING ANALYTES IN VARIOUS MATRICES SAFETY ASSOCIATES, INC. (US) 1999-04-29 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050240052-A1 Process for producing fluorine-containing alkylsulfonylaminoethyl a-substitued acrylate PFAS, AFF2, AFF1 MEN1 754/4885KMT2A 347/4885POLB 2585/4885
US-20050165249-A1 Process for producing alpha-substituted acrylic acid esters AFF1, ASS1, RER1 MEN1 1852/4885KMT2A 1571/4885POLB 1116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.