Astragalin

Astragalin

SCHEMBL23897

O=c1c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c(-c2ccc(O)cc2)oc2cc(O)cc(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HB P07237 5/20 1.00
AKR1B1 P15121 4/20 1.00
CA12 O43570 2/20 1.00
CA2 P00918 2/20 1.00
CA4 P22748 2/20 1.00
CA7 P43166 2/20 1.00
ACHE P22303 1/20 1.00
KDM4E B2RXH2 4/20 0.86
GAA P10253 4/20 0.86
POLB P06746 3/20 0.86
APEX1 P27695 1/20 0.86
RECQL P46063 1/20 0.86
EPHX2 P34913 4/20 0.86
MAPT P10636 2/20 0.86
ADRA2C P18825 1/20 0.86
NOX4 Q9NPH5 1/20 0.86
KDM1A O60341 1/20 0.86
SLCO2B1 O94956 1/20 0.86
ALPL P05186 1/20 0.86
HMGB1 P09429 1/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Astragalin SCHEMBL15144481 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4
Astragalin SCHEMBL23898 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4
Astragalin SCHEMBL11987406 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4
Astragalin SCHEMBL15147309 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4
Astragalin SCHEMBL572129 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4
Astragalin SCHEMBL18073780 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4
Astragalin SCHEMBL24008641 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4
Astragalin SCHEMBL19691768 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4
Astragalin SCHEMBL12710503 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4
Astragalin SCHEMBL31372889 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3450 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026102563-A1 DISUBSTITUTED PYRIMIDOPYRROLE ANALOG AND USE THEREOF 深圳湾实验室坪山生物医药研发转化中心 2026-05-21 WO claimed
EP-4378448-B1 EXTRACT OF FLOWERS, LEAVES AND/OR SEED PODS OF IMPATIENS AND LEAVES OF PANDANUS, IN DRIED AND LIQUID FORM, A METHOD OF ITS OBTAINING AND USE THEREOF PBCLABS SP Z O O (PL) 2026-05-20 EP claimed
EP-4743181-A1 POLYPHENOL-RICH DAMASK ROSE EXTRACT DERIVED FROM A HYDRODISTILLATION BYPRODUCT AND ITS USES AS A FOOD SUPPLEMENT Robertet S.A. (FR) 2026-05-20 EP claimed
CN-122063206-A Method for verifying uric acid reducing action mechanism of apocynum venetum leaf extract 山东航空学院 2026-05-19 CN claimed
CN-122042845-A Feature map for detecting basis of Yi-Shi-qing granular substances, construction method and application thereof 陕西科技大学 2026-05-15 CN claimed
EP-4514146-B1 A COMBINATION FOR USE IN THE PREPARATION OF A DRINKABLE FOAMING OR FOAMABLE LIQUID, A DEVICE AND A METHOD FOR PREPARING AND DISPENSING A DRINKABLE FOAMING OR FOAMABLE LIQUID BAR ON B V (BE) 2026-05-13 EP claimed
US-20260115112-A1 PARTICULATES OF POLYPHENOLICS AND DISPERSIONS THEREOF SOLESENCE INC (US) 2026-04-30 US claimed
EP-4714440-A2 A HEALING HERBAL-MINERAL COMPOSITION WITH ENHANCED EFFECTS Kurek, Janusz (PL) 2026-03-25 EP claimed
EP-3346842-B1 STABLE INOCULANT COMPOSITIONS AND METHODS FOR PRODUCING SAME NOVONESIS PLANT BIOSOLUTIONS AS (DK) 2026-03-25 EP claimed
US-12419317-B1 Plant derived food preservative IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY (SA) 2025-09-23 US claimed
US-20020115618-A1 Method and composition for the topical treatment of diabetic neuropathy QUIGLEY CORPORATION, THE 2002-08-22 US claimed
US-20020090403-A1 Antidepressant TOKIWA PHYTOCHEMICAL CO., LTD. (JP) 2002-07-11 US claimed
WO-2002049575-A2 METHOD AND COMPOSITION FOR THE TREATMENT OF DIABETIC NEUROPATHY THE QUIGLEY CORPORATION (US) 2002-06-27 WO claimed
CN-1068206-C Traditional Chinese medicine for resisting adverse reaction of adrenocortical hormone and compound preparation thereof MEDICINE SCIENCE & TECHNOLOGY (CN) 2001-07-11 CN claimed
WO-2001003687-A2 METHOD AND COMPOSITIONS FOR INHIBITING BIOSYNTHESIS OR BIOACTIVITY OF ENDOGENOUS STEROID SEX HORMONES IN HUMANS CEDARS-SINAI MEDICAL CENTER (US) 2001-01-18 WO claimed
CN-1144120-A Traditional Chinese medicine antagonist for adrenocortical hormone adverse reaction and compound preparation thereof MEDICINE SCIENCE & TECHNOLOGY (CN) 1997-03-05 CN claimed
EP-0633022-B1 Chondroprotective flavones KUREHA CHEMICAL IND CO LTD (JP) 1997-02-19 EP claimed
CN-1100633-A Chondroprotective agents KUREHA CHEMICAL IND CO LTD (JP) 1995-03-29 CN claimed
EP-0633022-A2 Chondroprotective flavones KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) 1995-01-11 EP claimed
EP-0257887-A2 Ophthalmic compositions HOUSTON BIOTECHNOLOGY INCORPORATED (US) 1988-03-02 EP claimed