Astragalin

Astragalin

SCHEMBL572129

O=c1c(OC2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c(-c2ccc(O)cc2)oc2cc(O)cc(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HB P07237 5/20 1.00
AKR1B1 P15121 4/20 1.00
CA12 O43570 2/20 1.00
CA2 P00918 2/20 1.00
CA4 P22748 2/20 1.00
CA7 P43166 2/20 1.00
ACHE P22303 1/20 1.00
KDM4E B2RXH2 4/20 0.86
GAA P10253 4/20 0.86
POLB P06746 3/20 0.86
APEX1 P27695 1/20 0.86
RECQL P46063 1/20 0.86
EPHX2 P34913 4/20 0.86
MAPT P10636 2/20 0.86
ADRA2C P18825 1/20 0.86
NOX4 Q9NPH5 1/20 0.86
KDM1A O60341 1/20 0.86
SLCO2B1 O94956 1/20 0.86
ALPL P05186 1/20 0.86
HMGB1 P09429 1/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Astragalin SCHEMBL15144481 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4
Astragalin SCHEMBL23898 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4
Astragalin SCHEMBL11987406 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4
Astragalin SCHEMBL15147309 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4
Astragalin SCHEMBL18073780 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4
Astragalin SCHEMBL24008641 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4
Astragalin SCHEMBL19691768 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4
Astragalin SCHEMBL23897 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4
Astragalin SCHEMBL12710503 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4
Astragalin SCHEMBL31372889 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 953 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250257331-A1 FLAVONOID GLYCOSIDE GLYCOSYLTRANSFERASE LbUGT71BX1 IN LAPORTEA BULBIFERA AS WELL AS THE CODING GENE AND THE USE THEREOF INST CHINESE MATERIA MEDICA CHINA ACADEMY OF CMS (CN) 2025-08-14 US claimed
CN-120119253-A High-stability titanium etching solution and preparation method and application thereof 浙江奥首材料科技有限公司 2025-06-10 CN claimed
CN-120025998-A Acyltransferase CsHCT, coding gene and application thereof 安徽农业大学 2025-05-23 CN claimed
US-20250051551-A1 IMPROVED POLYMER COMPOSITES WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2025-02-13 US claimed
CN-119371472-A Template molecule, molecularly imprinted polymer and application thereof in separation of natural flavonoid compounds 广州伽能生物科技有限公司 2025-01-28 CN claimed
CN-119302880-A Hybrid broussonetia papyrifera total flavone and extraction method, application and detection method thereof 河南省高新技术实业有限公司 2025-01-14 CN claimed
CN-119040355-A Tartary buckwheat-derived phosphokinase gene, and expression vector and application thereof 中国农业科学院作物科学研究所 2024-11-29 CN claimed
CN-108904343-B Ginkgo leaf composition for delaying aging and preparation method and application thereof 北京工商大学 2024-11-08 CN claimed
CN-118883755-A Quality detection method for blood lipid-reducing active ingredients of sea buckthorn leaf Fu tea 陕西中医药大学第二附属医院 2024-11-01 CN claimed
US-20240350574-A1 PHENOLIC PHYTOCHEMICALS FOR BONE METASTASIS OF CANCER NDSU RESEARCH FOUNDATION 2024-10-24 US claimed
WO-2002064536-A1 METHOD FOR EXTRACTING, FRACTIONATING AND PURIFYING POLYPHENOL COMPOUNDS ORIGINATING FROM FRESH VEGETABLE CULLS USING A HIGH-ABSORPTION AND -ELUTION RESIN INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA) (FR) 2002-08-22 WO claimed
EP-1172109-A9 COMPOSITIONS FOR PREVENTING AND TREATING TYPE I ALLERGY Sunstar Inc. (JP) 2002-04-03 EP claimed
CN-1325454-A Method for enzymatic decomposition of rutinosides MERCK PATENT GMBH (DE) 2001-12-05 CN claimed
CN-1258191-A Antimicrobial prevention and treatment of human immunodeficiency virus and other infectious diseases MERYL SQUIRES (US) 2000-06-28 CN claimed
EP-0980203-A1 ANTIMICROBIAL PREVENTION AND TREATMENT OF HUMAN IMMUNEDEFICIENCY VIRUS AND OTHER INFECTIOUS DISEASES Squires, Meryl (US) 2000-02-23 EP claimed
WO-1998042188-A1 ANTIMICROBIAL PREVENTION AND TREATMENT OF HUMAN IMMUNEDEFICIENCY VIRUS AND OTHER INFECTIOUS DISEASES SQUIRES MERYL (US) 1998-10-01 WO claimed
EP-0275005-B1 COMPLEX COMPOUNDS OF BIOFLAVONOIDS WITH PHOSPHOLIPIDS, THEIR PREPARATION AND USE, AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM INDENA S.p.A. (IT) 1993-08-11 EP claimed
US-5229116-A Administering a flavonoid or hypotensive EDGAR BOO E (SE) 1993-07-20 US claimed
EP-0431828-A1 Improvements relating to the administration of pharmaceutical agents Bailey, David G. (CA) 1991-06-12 EP claimed
WO-1990006104-A1 USE OF KAEMPFEROL AND CERTAIN DERIVATIVES THEREOF FOR THE PREPARATION OF A COSMETIC OR PHARMACEUTICAL COMPOSITION LVMH RECHERCHE (FR) 1990-06-14 WO claimed