Astragalin

Astragalin

SCHEMBL24008641

O=c1c(O[C@@H]2O[C@H](CO)C(O)[C@H](O)[C@H]2O)c(-c2ccc(O)cc2)oc2cc(O)cc(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HB P07237 5/20 1.00
AKR1B1 P15121 4/20 1.00
CA12 O43570 2/20 1.00
CA2 P00918 2/20 1.00
CA4 P22748 2/20 1.00
CA7 P43166 2/20 1.00
ACHE P22303 1/20 1.00
KDM4E B2RXH2 4/20 0.86
GAA P10253 4/20 0.86
POLB P06746 3/20 0.86
APEX1 P27695 1/20 0.86
RECQL P46063 1/20 0.86
EPHX2 P34913 4/20 0.86
MAPT P10636 2/20 0.86
ADRA2C P18825 1/20 0.86
NOX4 Q9NPH5 1/20 0.86
KDM1A O60341 1/20 0.86
SLCO2B1 O94956 1/20 0.86
ALPL P05186 1/20 0.86
HMGB1 P09429 1/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Astragalin SCHEMBL15144481 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4
Astragalin SCHEMBL23898 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4
Astragalin SCHEMBL11987406 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4
Astragalin SCHEMBL15147309 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4
Astragalin SCHEMBL572129 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4
Astragalin SCHEMBL18073780 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4
Astragalin SCHEMBL19691768 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4
Astragalin SCHEMBL23897 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4
Astragalin SCHEMBL12710503 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4
Astragalin SCHEMBL31372889 1.00 P4HB (1.00) P4HBAKR1B1CA12CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210346281-A1 MULTI-COMPONENT INJECTION TIANJIN CHASE SUN PHARMACEUTICAL CO. LTD (CN) 2021-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210346281-A1 MULTI-COMPONENT INJECTION SAMM50, IL6, ATP5MF P4HB 3539/4885AKR1B1 3130/4885CA12 3160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.