Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | GNRHR | P30968 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29976245 | 0.90 | GNRHR (0.37) | ALDH1A1GNRHRKDM4ETP53KMT2A | |
| SCHEMBL28910497 | 0.90 | GNRHR (0.37) | ALDH1A1GNRHRKDM4ETP53KMT2A | |
| SCHEMBL20985703 | 0.88 | GNRHR (0.33) | ALDH1A1GNRHRMAPK1KDM4ETDP1 | |
| SCHEMBL21020131 | 0.85 | TP53 (0.33) | ALDH1A1GNRHRMAPK1KDM4ETDP1 | |
| SCHEMBL21019479 | 0.84 | TP53 (0.34) | ALDH1A1GNRHRTP53KMT2APDE5A | |
| SCHEMBL19806107 | 0.82 | GNRHR (0.36) | ALDH1A1GNRHRKDM4ETP53KMT2A | |
| SCHEMBL30526076 | 0.82 | GNRHR (0.36) | ALDH1A1GNRHRKDM4ETP53KMT2A | |
| SCHEMBL19805644 | 0.82 | TP53 (0.35) | ALDH1A1GNRHRKDM4ETP53KMT2A | |
| SCHEMBL21019776 | 0.82 | GNRHR (0.34) | ALDH1A1GNRHRTP53KMT2AMEN1 | |
| SCHEMBL19805615 | 0.82 | GNRHR (0.36) | ALDH1A1GNRHRTP53KMT2APDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210309647-A1 | Apoptosis Inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210309647-A1 | Apoptosis Inhibitors | BAX, SDHA, SDHB | ALDH1A1 550/4885GNRHR 3014/4885MAPK1 2753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.