Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28910497 | 1.00 | GNRHR (0.37) | GNRHRTP53MAPTLMNANPSR1 | |
| SCHEMBL23897425 | 0.90 | ALDH1A1 (0.34) | GNRHRTP53MAPTLMNANPSR1 | |
| SCHEMBL19806107 | 0.89 | GNRHR (0.36) | GNRHRTP53MAPTALDH1A1HTT | |
| SCHEMBL30526076 | 0.89 | GNRHR (0.36) | GNRHRTP53MAPTALDH1A1HTT | |
| SCHEMBL28910485 | 0.89 | GNRHR (0.34) | GNRHRTP53 | |
| SCHEMBL29976113 | 0.89 | GNRHR (0.34) | GNRHRTP53 | |
| SCHEMBL19806023 | 0.86 | GNRHR (0.36) | GNRHRTP53MAPTLMNAALDH1A1 | |
| SCHEMBL29976275 | 0.86 | GNRHR (0.36) | GNRHRTP53MAPTLMNAALDH1A1 | |
| SCHEMBL19805644 | 0.85 | TP53 (0.35) | GNRHRTP53ALDH1A1KMT2AEGFR | |
| SCHEMBL21019917 | 0.85 | GNRHR (0.34) | GNRHRTP53MAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |