⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27251551 | 0.84 | MAPT (0.32) | — | |
| SCHEMBL23900852 | 0.83 | — | — | |
| SCHEMBL23900402 | 0.67 | MGLL (0.35) | — | |
| SCHEMBL14459659 | 0.61 | LMNA (0.31) | — | |
| SCHEMBL23900597 | 0.59 | — | — | |
| SCHEMBL23900561 | 0.58 | — | — | |
| SCHEMBL19803193 | 0.56 | — | — | |
| SCHEMBL11930009 | 0.56 | KDM4E (0.48) | — | |
| SCHEMBL4784890 | 0.55 | TSHR (0.30) | — | |
| SCHEMBL19957977 | 0.55 | MGLL (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024075080-A1 | NEODEGRADER CONJUGATES | ORUM THERAPEUTICS, INC. (KR) | 2024-04-11 | — | — | WO | disclosed |
| WO-2021198965-A1 | NEODEGRADER CONJUGATES | ORUM THERAPEUTICS, INC. (KR) | 2021-10-07 | — | — | WO | disclosed |