Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2391355 | 0.83 | PLA2G1B (0.34) | KDM4EHTTPTGER4PTGER3PTGER2 | |
| SCHEMBL6023587 | 0.83 | HTT (0.56) | KDM4EHTTPTGER4PTGER3PTGER2 | |
| SCHEMBL9518819 | 0.76 | NFKB1 (0.50) | KDM4EPTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL9447846 | 0.75 | NFKB1 (0.61) | KDM4EHTTPTGER4PTGER3PTGER2 | |
| SCHEMBL2131313 | 0.74 | DRD2 (0.41) | DRD2HTR1DDRD3 | |
| SCHEMBL6317948 | 0.71 | PLA2G1B (0.39) | KDM4EHTTPTGER4PTGER3PTGER2 | |
| SCHEMBL6317945 | 0.71 | PLA2G1B (0.39) | KDM4EHTTPTGER4PTGER3PTGER2 | |
| SCHEMBL2865033 | 0.71 | CA1 (0.47) | KDM4EHTTPTGER4PTGER3PTGER2 | |
| SCHEMBL6855197 | 0.71 | CA1 (0.47) | KDM4EHTTPTGER4PTGER3PTGER2 | |
| SCHEMBL15950027 | 0.71 | CA1 (0.46) | KDM4EHTTPTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE42700-E1 | Induction of apoptosis in cancer cells | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2011-09-13 | — | — | US | disclosed |