Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CPT1A | P50416 | 1/20 | 0.32 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6317945 | 0.85 | PLA2G1B (0.39) | PLA2G1BMAPTATG4BKDM4EALDH1A1 | |
| SCHEMBL6317948 | 0.85 | PLA2G1B (0.39) | PLA2G1BMAPTATG4BKDM4EALDH1A1 | |
| SCHEMBL2390113 | 0.83 | KDM4E (0.43) | KDM4EGAACA1CA2NFKB1 | |
| SCHEMBL2391055 | 0.79 | AKR1C3 (0.44) | PLA2G1BMAPTATG4BKDM4EALDH1A1 | |
| SCHEMBL6198235 | 0.76 | ALDH1A1 (0.38) | MAPTKDM4EALDH1A1GAACA1 | |
| SCHEMBL9515758 | 0.75 | PTGER3 (0.43) | PLA2G1BMAPTATG4BKDM4EALDH1A1 | |
| SCHEMBL2388955 | 0.75 | ESR1 (0.47) | MAPTKDM4EALDH1A1GAAESR1 | |
| SCHEMBL9515747 | 0.75 | PTGER3 (0.43) | PLA2G1BMAPTATG4BKDM4EALDH1A1 | |
| SCHEMBL6023587 | 0.72 | HTT (0.56) | PLA2G1BMAPTATG4BKDM4EGAA | |
| SCHEMBL6855197 | 0.72 | CA1 (0.47) | MAPTKDM4EALDH1A1GAAESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE42700-E1 | Induction of apoptosis in cancer cells | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2011-09-13 | — | — | US | disclosed |