Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | UBE2N | P61088 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KARS1 | Q15046 | 5/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL902067 | 0.84 | MTOR (0.54) | MTORSMG1KDM4ERAD52UBE2N | |
| SCHEMBL2385606 | 0.76 | HRH4 (0.58) | KDM4ERAD52UBE2NL3MBTL1HRH4 | |
| SCHEMBL1704214 | 0.76 | KARS1 (0.77) | MTORSMG1KARS1 | |
| SCHEMBL15344219 | 0.75 | RAD52 (0.55) | MTORSMG1KDM4ERAD52UBE2N | |
| SCHEMBL421349 | 0.75 | HTR3A (0.66) | KDM4EHRH4HTR3AHRH3 | |
| SCHEMBL30895935 | 0.75 | HTR3A (0.66) | KDM4EHRH4HTR3AHRH3 | |
| SCHEMBL15340858 | 0.75 | KDM4E (0.52) | MTORSMG1KDM4ERAD52UBE2N | |
| SCHEMBL15509065 | 0.74 | HRH4 (0.59) | KDM4ERAD52UBE2NL3MBTL1HRH4 | |
| Hydrochloric Acid SCHEMBL9131760 | 0.74 | HTR3A (0.64) | KDM4EHRH4HTR3AHRH3 | |
| SCHEMBL26176286 | 0.73 | DYRK1A (0.51) | MTORSMG1KDM4ERAD52UBE2N |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916771-B | Multi-target antitumor compound and preparation method and application thereof | 浙江华海药业股份有限公司 | 2025-04-01 | — | — | CN | disclosed |
| WO-2021197467-A1 | MULTI-TARGET ANTI-TUMOR COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海华汇拓医药科技有限公司 | 2021-10-07 | — | — | WO | disclosed |