SCHEMBL23901442

SCHEMBL23901442

COc1cc(C(=O)NP(c2c(OC)cccc2OC)c2c(OC)cccc2OC)cc(OC)c1OC

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.51
MEN1 O00255 5/20 0.51
ABCB1 P08183 1/20 0.50
KDM4E B2RXH2 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
ALDH1A1 P00352 1/20 0.49
MAPT P10636 1/20 0.49
HSD17B10 Q99714 1/20 0.48
SMO Q99835 1/20 0.48
POLB P06746 1/20 0.48
HPGD P15428 1/20 0.48
LMNA P02545 1/20 0.48
PKM P14618 1/20 0.48
MAPK1 P28482 1/20 0.48
BRD4 O60885 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23901441 0.84 RAB9A (0.54) KMT2AMEN1KDM4ESMN1; SMN2ALDH1A1
SCHEMBL23901444 0.82 RAF1 (0.47) KDM4EMAPTPOLB
SCHEMBL23883169 0.74 NPC1 (0.52) KMT2AMEN1KDM4ESMN1; SMN2ALDH1A1
SCHEMBL16677971 0.73 MAPT (0.67) KMT2AMEN1ABCB1KDM4ESMN1; SMN2
SCHEMBL4143482 0.73 ALDH1A1 (0.77) KMT2AMEN1ABCB1ALDH1A1MAPT
SCHEMBL1437082 0.73 MEN1 (0.62) KMT2AMEN1ABCB1ALDH1A1MAPT
SCHEMBL23883572 0.73 CA1 (0.44) KDM4ESMN1; SMN2ALDH1A1MAPTHSD17B10
SCHEMBL14985428 0.72 KDM4E (0.66) KMT2AMEN1KDM4ESMN1; SMN2ALDH1A1
SCHEMBL707585 0.72 MEN1 (0.89) KMT2AMEN1ABCB1KDM4ESMN1; SMN2
SCHEMBL6497794 0.72 MEN1 (0.60) KMT2AMEN1ABCB1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115335419-B Sterically hindered phosphine-amide supported nickel (II) or palladium (II) catalysts for the copolymerization of ethylene and polar comonomers 陶氏环球技术有限责任公司 2024-10-25 CN disclosed
US-20230132484-A1 STERICALLY HINDERED PHOSPHINE-AMIDE SUPPORTED NICKEL (II) OR PALLADIUM (II) CATALYSTS FOR THE COPOLYMERIZATION OF ETHYLENE AND POLAR COMONOMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2023-05-04 US disclosed
US-20230132484-A1 STERICALLY HINDERED PHOSPHINE-AMIDE SUPPORTED NICKEL (II) OR PALLADIUM (II) CATALYSTS FOR THE COPOLYMERIZATION OF ETHYLENE AND POLAR COMONOMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2023-05-04 US disclosed
EP-4126992-A1 STERICALLY HINDERED PHOSPHINE-AMIDE SUPPORTED NICKEL(II) OR PALLADIUM(II) CATALYSTS FOR THE COPOLYMERIZATION OF ETHYLENE AND POLAR COMONOMERS Dow Global Technologies LLC (US) 2023-02-08 EP disclosed
WO-2021202714-A1 STERICALLY HINDERED PHOSPHINE-AMIDE SUPPORTED NICKEL(II) OR PALLADIUM(II) CATALYSTS FOR THE COPOLYMERIZATION OF ETHYLENE AND POLAR COMONOMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2021-10-07 WO disclosed