Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.54 |
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23901442 | 0.84 | KMT2A (0.51) | KMT2AMEN1POLBSMN1; SMN2KDM4E | |
| SCHEMBL23901444 | 0.79 | RAF1 (0.47) | POLBMAOBKDM4ENPSR1MAPT | |
| SCHEMBL23883169 | 0.76 | NPC1 (0.52) | RAB9ANPC1KMT2AMEN1POLB | |
| SCHEMBL23883572 | 0.75 | CA1 (0.44) | RAB9ANPC1KCNK3KCNK9POLB | |
| SCHEMBL30601527 | 0.73 | KCNK3 (0.56) | RAB9ANPC1KCNK3KCNK9KMT2A | |
| SCHEMBL22439097 | 0.73 | KCNK3 (0.56) | RAB9ANPC1KCNK3KCNK9KMT2A | |
| SCHEMBL30129532 | 0.73 | TUBB4A (0.44) | KMT2AMEN1POLBHTTSMN1; SMN2 | |
| SCHEMBL23883575 | 0.73 | TUBB4A (0.44) | KMT2AMEN1POLBHTTSMN1; SMN2 | |
| SCHEMBL22624859 | 0.72 | RAB9A (0.63) | RAB9ANPC1KCNK3KCNK9KMT2A | |
| SCHEMBL527994 | 0.71 | RAB9A (0.77) | RAB9ANPC1KMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335419-B | Sterically hindered phosphine-amide supported nickel (II) or palladium (II) catalysts for the copolymerization of ethylene and polar comonomers | 陶氏环球技术有限责任公司 | 2024-10-25 | — | — | CN | disclosed |
| US-20230132484-A1 | STERICALLY HINDERED PHOSPHINE-AMIDE SUPPORTED NICKEL (II) OR PALLADIUM (II) CATALYSTS FOR THE COPOLYMERIZATION OF ETHYLENE AND POLAR COMONOMERS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-05-04 | — | — | US | disclosed |
| US-20230132484-A1 | STERICALLY HINDERED PHOSPHINE-AMIDE SUPPORTED NICKEL (II) OR PALLADIUM (II) CATALYSTS FOR THE COPOLYMERIZATION OF ETHYLENE AND POLAR COMONOMERS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-05-04 | — | — | US | disclosed |
| EP-4126992-A1 | STERICALLY HINDERED PHOSPHINE-AMIDE SUPPORTED NICKEL(II) OR PALLADIUM(II) CATALYSTS FOR THE COPOLYMERIZATION OF ETHYLENE AND POLAR COMONOMERS | Dow Global Technologies LLC (US) | 2023-02-08 | — | — | EP | disclosed |
| WO-2021202714-A1 | STERICALLY HINDERED PHOSPHINE-AMIDE SUPPORTED NICKEL(II) OR PALLADIUM(II) CATALYSTS FOR THE COPOLYMERIZATION OF ETHYLENE AND POLAR COMONOMERS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-10-07 | — | — | WO | disclosed |