Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 13/20 | 0.50 |
| ▸ | CTSV | O60911 | 12/20 | 0.50 |
| ▸ | CTSS | P25774 | 12/20 | 0.50 |
| ▸ | CTSK | P43235 | 8/20 | 0.50 |
| ▸ | CTSB | P07858 | 8/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21400205 | 0.87 | PNMT (0.51) | PNMTCTSLCTSVCTSSCTSK | |
| SCHEMBL805207 | 0.85 | CTSL (0.52) | PNMTCTSLCTSVCTSSCTSK | |
| SCHEMBL16287362 | 0.85 | CTSL (0.52) | PNMTCTSLCTSVCTSSCTSK | |
| SCHEMBL31369749 | 0.85 | CTSL (0.52) | PNMTCTSLCTSVCTSSCTSK | |
| SCHEMBL29539732 | 0.85 | CTSL (0.52) | PNMTCTSLCTSVCTSSCTSK | |
| Hydrochloric Acid SCHEMBL16289133 | 0.84 | CTSL (0.51) | PNMTCTSLCTSVCTSSCTSK | |
| SCHEMBL13957285 | 0.84 | MME (0.60) | CTSLCTSSCTSKCTSBFOLH1 | |
| SCHEMBL8254871 | 0.83 | MAPK1 (0.55) | PNMTCTSLCTSVCTSSCTSK | |
| SCHEMBL5870478 | 0.83 | MAPK1 (0.55) | PNMTCTSLCTSVCTSSCTSK | |
| SCHEMBL123574 | 0.82 | MME (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230143470-A1 | SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ | NATIONAL INSTITUTES OF HEALTH | 2023-05-11 | — | — | US | disclosed |
| US-20230143470-A1 | SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ | NATIONAL INSTITUTES OF HEALTH | 2023-05-11 | — | — | US | disclosed |
| WO-2021202600-A1 | SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230143470-A1 | SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ | HAVCR2, CD44, ENGASE | PNMT 3397/4885CTSL 531/4885CTSV 332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.