SCHEMBL805207

SCHEMBL805207

CN[C@@H](Cc1cccc(Cl)c1)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CTSL P07711 12/20 0.52
CTSV O60911 11/20 0.52
CTSS P25774 11/20 0.52
CTSB P07858 8/20 0.52
CTSK P43235 8/20 0.52
PNMT P11086 1/20 0.51
MAPK1 P28482 1/20 0.49
CTBP2 P56545 1/20 0.49
FOLH1 Q04609 1/20 0.48
FPR2 P25090 1/20 0.47
TAAR1 Q96RJ0 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16287362 1.00 CTSL (0.52) CTSLCTSVCTSSCTSBCTSK
SCHEMBL31369749 1.00 CTSL (0.52) CTSLCTSVCTSSCTSBCTSK
SCHEMBL29539732 1.00 CTSL (0.52) CTSLCTSVCTSSCTSBCTSK
Hydrochloric Acid SCHEMBL16289133 0.98 CTSL (0.51) CTSLCTSVCTSSCTSBCTSK
SCHEMBL14898396 0.88 PNMT (0.51) CTSLCTSVCTSSCTSBCTSK
SCHEMBL14942915 0.88 PNMT (0.51) CTSLCTSVCTSSCTSBCTSK
SCHEMBL21837394 0.85 TAAR1 (0.51) MAPK1FOLH1TAAR1
SCHEMBL21837393 0.85 TAAR1 (0.51) MAPK1FOLH1TAAR1
SCHEMBL23901512 0.85 PNMT (0.53) CTSLCTSVCTSSCTSBCTSK
SCHEMBL11134765 0.85 CTSL (0.50) CTSLCTSVCTSSCTSBCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025100520-A1 PEPTIDE, PEPTIDE COMPLEX, PHARMACEUTICAL COMPOSITION, COMPOSITION FOR CELL CULTURE, AND COMPOSITION FOR MEDICAL USE, DIAGNOSTIC USE, OR RESEARCH USE ペプチドリーム株式会社 2025-05-15 WO claimed
US-12637494-B2 Method for producing peptide containing non-natural amino acid CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2026-05-26 US disclosed
EP-4667483-A1 HUMAN TRANSFERRIN RECEPTOR-BINDING PEPTIDE JCR Pharmaceuticals Co., Ltd. (JP) 2025-12-24 EP disclosed
US-20250361274-A1 PEPTIDE AND PEPTIDE-CONTAINING AGENT PEPTIDREAM INC. (JP) 2025-11-27 US disclosed
EP-4628592-A1 PEPTIDE PRODUCTION METHOD COMPRISING STEP FOR TRANSLATING AMINO ACID HAVING OXYGEN ATOM AT SPECIFIC POSITION CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-10-08 EP disclosed
US-12415835-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-16 US disclosed
US-12391971-B2 Method for synthesizing peptides in cell-free translation system CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-08-19 US disclosed
EP-4570371-A2 METHOD FOR PRODUCING CYCLIC ORGANIC COMPOUND Chugai Seiyaku Kabushiki Kaisha (JP) 2025-06-18 EP disclosed
WO-2025100520-A1 PEPTIDE, PEPTIDE COMPLEX, PHARMACEUTICAL COMPOSITION, COMPOSITION FOR CELL CULTURE, AND COMPOSITION FOR MEDICAL USE, DIAGNOSTIC USE, OR RESEARCH USE ペプチドリーム株式会社 2025-05-15 WO disclosed
EP-4541805-A1 PEPTIDE AND PEPTIDE-CONTAINING AGENT PeptiDream Inc. (JP) 2025-04-23 EP disclosed
EP-2813512-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD Chugai Seiyaku Kabushiki Kaisha (JP) 2014-12-17 EP disclosed
EP-2813512-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD Chugai Seiyaku Kabushiki Kaisha (JP) 2014-12-17 EP disclosed
WO-2013100132-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD 中外製薬株式会社 (JP) 2013-07-04 WO disclosed
US-20120071329-A1 METHODS FOR IDENTIFYING COMPOUNDS OF INTEREST USING ENCODED LIBRARIES GLAXOSMITHKLINE LLC (US) 2012-03-22 US disclosed
US-20090062147-A1 Methods for synthesis of encoded libraries PRAECIS PHARMACEUTICALS INCORPORATED (US) 2009-03-05 US disclosed
US-7253198-B2 Hydroxyethylamine derivatives for the treatment of Alzheimer's disease GLAXO GROUP LIMITED (GB) 2007-08-07 US disclosed
EP-1567488-B1 HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE GLAXO GROUP LTD (GB) 2007-02-21 EP disclosed
US-20060025459-A1 Hydroxyethylamine derivatives for the treatment of alzheimer's disease GLAXO GROUP LIMITED (GB) 2006-02-02 US disclosed
EP-1567488-A1 HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE GLAXO GROUP LIMITED (GB) 2005-08-31 EP disclosed
WO-2004050619-A1 HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE GLAXO GROUP LIMITED (GB) 2004-06-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637494-B2 Method for producing peptide containing non-natural amino acid MRPL21, RPL21, RPL30 CTSL 886/4885CTSV 1431/4885CTSS 1597/4885
US-12391971-B2 Method for synthesizing peptides in cell-free translation system AARS1, NSUN3, RNGTT CTSL 691/4885CTSV 848/4885CTSS 481/4885
US-20060025459-A1 Hydroxyethylamine derivatives for the treatment of alzheimer's disease BACE2, PSEN2, BACE1 CTSL 975/4885CTSV 457/4885CTSS 313/4885
US-20250361274-A1 PEPTIDE AND PEPTIDE-CONTAINING AGENT BMP4, BMP1, BMPR2 CTSL 1777/4885CTSV 3711/4885CTSS 3416/4885
US-12415835-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R CTSL 120/4885CTSV 295/4885CTSS 273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.