Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18263396 | 0.88 | DPP4 (0.44) | MAPTALDH1A1GFERSMN1; SMN2MEN1 | |
| SCHEMBL4169509 | 0.86 | MAPT (0.61) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4170680 | 0.84 | MAPT (0.59) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL23901548 | 0.82 | MAPT (0.48) | MAPTALDH1A1GFERSMN1; SMN2MEN1 | |
| SCHEMBL4169516 | 0.81 | SOS1 (0.46) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL25453972 | 0.81 | HTR6 (0.44) | MAPTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL8264511 | 0.80 | MAPT (0.68) | MAPTALDH1A1GFERSMN1; SMN2MEN1 | |
| SCHEMBL3844453 | 0.79 | DRD2 (0.58) | MAPTALDH1A1GFERSMN1; SMN2MEN1 | |
| SCHEMBL1911855 | 0.79 | DPP4 (0.53) | MAPTALDH1A1LMNADPP4SUV39H2 | |
| SCHEMBL31669276 | 0.79 | KHK (0.48) | DPP4SUV39H2HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021202600-A1 | SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-10-07 | — | — | WO | disclosed |