Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 10/20 | 0.52 |
| ▸ | MC4R | P32245 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23901886 | 0.86 | NISCH (0.48) | NISCHMC4RMAOBKCNH2PDCD1LG2 | |
| SCHEMBL23566307 | 0.84 | NISCH (0.50) | NISCHMC4RMAOBKDM4E | |
| SCHEMBL23901905 | 0.84 | NISCH (0.50) | NISCHMC4RMAOBKDM4EPDCD1LG2 | |
| Hydrochloric Acid SCHEMBL23880715 | 0.83 | NISCH (0.49) | NISCHMC4RMAOBKDM4E | |
| SCHEMBL23902203 | 0.82 | NISCH (0.48) | NISCHMC4RMAOBKDM4EPDCD1LG2 | |
| SCHEMBL23902209 | 0.82 | NISCH (0.48) | NISCHMC4RMAOBKDM4EPDCD1LG2 | |
| Hydrochloric Acid SCHEMBL23880717 | 0.81 | NISCH (0.47) | NISCHMC4RMAOBKDM4EPDCD1LG2 | |
| SCHEMBL23902226 | 0.78 | NISCH (0.60) | NISCH | |
| SCHEMBL23901804 | 0.77 | RUVBL1 (0.44) | NISCHMC4RMAOB | |
| Hydrochloric Acid SCHEMBL23235807 | 0.77 | NISCH (0.58) | NISCHMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210309641-A1 | AMIDINES AND AMIDINE ANALOGS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION ANTIBIOTICS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2021-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210309641-A1 | AMIDINES AND AMIDINE ANALOGS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION ANTIBIOTICS | PAM, AMPD1, AMPD3 | NISCH 24/4885MC4R 3733/4885MAOB 2311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.