Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.55 |
| ▸ | F2 | P00734 | 5/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | PTPRF | P10586 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.45 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.45 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23235790 | 0.98 | PARP10 (0.55) | PARP10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL14280106 | 0.83 | MAOB (0.58) | PARP10PRSS1PRSS2PRSS3F2 | |
| Hydrochloric Acid SCHEMBL26633553 | 0.82 | MAOB (0.56) | PARP10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL23566019 | 0.81 | PRSS1 (0.84) | PARP10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL23902235 | 0.80 | NPC1 (0.49) | PRSS1F2MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL23235822 | 0.80 | PRSS1 (0.81) | PARP10PRSS1PRSS2PRSS3F2 | |
| Hydrochloric Acid SCHEMBL23541197 | 0.80 | PRSS1 (0.81) | PARP10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL23901931 | 0.79 | PARP10 (0.56) | PARP10PRSS1PRSS2PRSS3F2 | |
| Hydrochloric Acid SCHEMBL23880735 | 0.78 | DGAT1 (0.44) | PARP10PRSS1F2PTPN1DGAT1 | |
| SCHEMBL23566457 | 0.77 | PARP10 (0.51) | PARP10PRSS1PRSS2PRSS3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210309641-A1 | AMIDINES AND AMIDINE ANALOGS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION ANTIBIOTICS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2021-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210309641-A1 | AMIDINES AND AMIDINE ANALOGS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION ANTIBIOTICS | PAM, AMPD1, AMPD3 | PARP10 1888/4885PRSS1 652/4885PRSS2 1318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.