Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 5/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23070805 | 0.87 | PKM (0.42) | MEN1KMT2AOPRD1OPRK1ACKR3 | |
| SCHEMBL23070897 | 0.86 | PKM (0.42) | MEN1KMT2AOPRD1OPRK1ACKR3 | |
| SCHEMBL23070900 | 0.85 | MEN1 (0.40) | MEN1KMT2AOPRD1OPRK1ACKR3 | |
| SCHEMBL22493598 | 0.83 | MEN1 (0.48) | MEN1KMT2APKMPOLBSMN1; SMN2 | |
| SCHEMBL22770369 | 0.79 | PKM (0.40) | MEN1KMT2AOPRD1OPRK1ACKR3 | |
| SCHEMBL13512956 | 0.75 | MEN1 (0.56) | MEN1KMT2AOPRD1OPRK1USP2 | |
| SCHEMBL1118114 | 0.74 | ACKR3 (0.41) | OPRD1OPRK1ACKR3ACACBNAMPT | |
| SCHEMBL18921641 | 0.72 | GPR119 (0.53) | MEN1KMT2AOPRD1OPRK1NAMPT | |
| SCHEMBL15348951 | 0.72 | F2RL3 (0.48) | OPRD1OPRK1ACKR3ACACBNAMPT | |
| SCHEMBL28695801 | 0.72 | POLB (0.58) | MEN1KMT2AOPRD1OPRK1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021197452-A1 | CRYSTAL FORM OF FREE ALKALI OF NITROGEN-CONTAINING AROMATIC DERIVATIVES | 上海翰森生物医药科技有限公司 | 2021-10-07 | — | — | WO | disclosed |