Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23880737 | 0.99 | FFAR4 (0.43) | FFAR4FFAR1MRGPRX4TAS1R3TAS1R1 | |
| SCHEMBL23902221 | 0.88 | RAB9A (0.47) | MRGPRX4ALDH1A1HPGDHTTPRSS1 | |
| Hydrochloric Acid SCHEMBL23880744 | 0.86 | RAB9A (0.46) | MRGPRX4ALDH1A1HPGDHTTPRSS1 | |
| SCHEMBL23901802 | 0.85 | FFAR4 (0.47) | FFAR4FFAR1MRGPRX4TAS1R3TAS1R1 | |
| Hydrochloric Acid SCHEMBL23235737 | 0.84 | FFAR4 (0.46) | FFAR4FFAR1MRGPRX4TAS1R3TAS1R1 | |
| SCHEMBL23902311 | 0.83 | FFAR4 (0.45) | FFAR4FFAR1MRGPRX4TAS1R3TAS1R1 | |
| SCHEMBL23566129 | 0.83 | PARP10 (0.52) | PARP10ALDH1A1PRSS1PRSS2PRSS3 | |
| SCHEMBL23902312 | 0.83 | PARP10 (0.43) | FFAR1MRGPRX4PARP10ALDH1A1PRSS1 | |
| Hydrochloric Acid SCHEMBL23235788 | 0.82 | FFAR4 (0.44) | FFAR4FFAR1MRGPRX4TAS1R3TAS1R1 | |
| Hydrochloric Acid SCHEMBL29741543 | 0.82 | PARP10 (0.51) | PARP10ALDH1A1PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210309641-A1 | AMIDINES AND AMIDINE ANALOGS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION ANTIBIOTICS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2021-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210309641-A1 | AMIDINES AND AMIDINE ANALOGS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION ANTIBIOTICS | PAM, AMPD1, AMPD3 | FFAR4 2035/4885FFAR1 2920/4885MRGPRX4 546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.