SCHEMBL2390196

SCHEMBL2390196

O=C(c1ccc(Cl)cc1)C1(Cl)C=CC=CC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CES2 O00748 3/20 0.39
CES1 P23141 3/20 0.39
TSHR P16473 2/20 0.38
ALOX15 P16050 1/20 0.38
MAPK1 P28482 2/20 0.35
GSK3B P49841 2/20 0.35
SRD5A2 P31213 1/20 0.35
HPGD P15428 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.34
CYP3A4 P08684 1/20 0.34
ATM Q13315 1/20 0.34
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27981573 0.85 LMNA (0.40) CA1CA2CES2CES1TSHR
SCHEMBL512998 0.82 ALDH1A1 (0.42) CES2CES1SRD5A2CYP3A4ATM
SCHEMBL14062032 0.77 SERPINE1 (0.41) SRD5A2ALDH1A1LMNAMAPTMEN1
SCHEMBL6687771 0.75 PPARA (0.49) TSHRCYP3A4ALDH1A1KDM4ELMNA
SCHEMBL9419970 0.74 CES2 (0.43) CES2CES1HPGDALDH1A1MAPT
SCHEMBL10886027 0.72
SCHEMBL10945618 0.70
SCHEMBL3474364 0.70
SCHEMBL5073219 0.69 CES2 (0.42) CES2CES1TSHRALOX15MAPK1
SCHEMBL18338013 0.69 CES2 (0.50) CA1CA2CES2CES1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7750091-B2 Foam that is a blend of a polyphenylene with units derived from p-dichlorobenzophenone and m-dichlorobenzene and a polyphenyl ether sulfone with p,p'-biphenyl and diphenyl sulfone units; useful in numerous applications such as in the preparation of articles and of foams having reduced density SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2010-07-06 US claimed
EP-1858977-B1 POLYPHENYLENE-POLY(ARYL ETHER SULFONE) BLENDS, ARTICLES AND METHOD SOLVAY ADVANCED POLYMERS LLC (US) 2009-06-10 EP claimed
US-20080293840-A1 POLYPHENYLENE-POLY(ARYL ETHER SULFONE) BLENDS, ARTICLES AND METHOD SOLVAY ADVANCED POLYMERS L.L.C. (US) 2008-11-27 US claimed
EP-1858977-A2 POLYPHENYLENE-POLY(ARYL ETHER SULFONE) BLENDS, ARTICLES AND METHOD Solvay Advanced Polymers, L.L.C. (US) 2007-11-28 EP claimed
WO-2006094988-A2 POLYPHENYLENE-POLY(ARYL ETHER SULFONE) BLENDS, ARTICLES AND METHOD SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2006-09-14 WO claimed
CN-109564322-B Identification display medium and method for manufacturing same 日本瑞翁株式会社 2022-08-02 CN disclosed
US-20200048426-A1 INORGANIC TUBULAR-LIKE PARTICLES IN A POLYMER MATRIX Nanotech Industrial Solutions, Inc. 2020-02-13 US disclosed
EP-2205289-B1 MEDICAL TUBINGS MADE OF A POLYMER MATERIAL SOLVAY SPECIALTY POLYMERS USA (US) 2019-01-02 EP disclosed
EP-2547383-B1 IMPROVED NEEDLES MADE OF A PARTICULAR PLASTIC MATERIAL SOLVAY SPECIALTY POLYMERS USA L L C (US) 2018-07-18 EP disclosed
US-20180057659-A1 THERMALLY STABILIZED POLYARYLENE COMPOSITIONS SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2018-03-01 US disclosed
EP-2413984-B1 FASTENERS MADE OF A POLYMER MATERIAL SOLVAY SPECIALTY POLYMERS USA (US) 2017-08-23 EP disclosed
US-9539361-B2 Prosthetic devices SOLVAY SPECIALTY POLYMERS USA, L.L.C. (US) 2017-01-10 US disclosed
WO-2007101857-A2 NEW POLYARYLENE COMPOSITION SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2007-09-13 WO disclosed
WO-2007101845-A2 NEW USE OF A KINKED RIGID-ROD POLYARYLENE, AND ARTICLES MADE FROM SAID KINKED RIGID-ROD POLYARYLENE SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2007-09-13 WO disclosed
WO-2007101858-A2 NEW AROMATIC POLYIMIDE COMPOSITION SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2007-09-13 WO disclosed
WO-2007101852-A2 NEW POLYARYLENE COMPOSITION AND ARTICLES MADE THEREFROM SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2007-09-13 WO disclosed
WO-2006094988-A2 POLYPHENYLENE-POLY(ARYL ETHER SULFONE) BLENDS, ARTICLES AND METHOD SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2006-09-14 WO disclosed
US-6912370-B2 Dual sided image printing device and method RICOH COMPANY, LTD. (JP) 2005-06-28 US disclosed
US-5089597-A Heating, liquefaction of resin particles in slurry, adding separation agent, cooling, solidification yields particles with high bulk density; dustless PHILLIPS PETROLEUM COMPANY (US) 1992-02-18 US disclosed
EP-0339621-A2 Method to recover granular poly(arylene sulfide ketone) and poly(arylene sulfide diketone) by a liquid quench process PHILLIPS PETROLEUM COMPANY (US) 1989-11-02 EP disclosed