Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23903155 | 0.80 | SMN1; SMN2 (0.56) | NPC1RAB9AKDM4ETP53SMN1; SMN2 | |
| SCHEMBL23903104 | 0.79 | NPC1 (0.54) | NPC1RAB9A | |
| SCHEMBL23902934 | 0.78 | NPC1 (0.51) | NPC1RAB9ACASP3SENP7SENP6 | |
| SCHEMBL26227050 | 0.76 | NPC1 (0.48) | NPC1RAB9AKDM4ETP53SMN1; SMN2 | |
| SCHEMBL26226924 | 0.75 | SMN1; SMN2 (0.52) | NPC1RAB9AKDM4ETP53SMN1; SMN2 | |
| SCHEMBL26228072 | 0.73 | SMN1; SMN2 (0.50) | NPC1RAB9AKDM4ETP53SMN1; SMN2 | |
| SCHEMBL25501050 | 0.73 | KDM4E (0.52) | NPC1RAB9AKDM4ETP53SMN1; SMN2 | |
| SCHEMBL26226986 | 0.72 | NPC1 (0.58) | NPC1RAB9AKDM4ESMN1; SMN2LMNA | |
| SCHEMBL25501209 | 0.71 | RAB9A (0.54) | NPC1RAB9AKDM4ETP53SMN1; SMN2 | |
| SCHEMBL26227181 | 0.71 | SMN1; SMN2 (0.50) | NPC1RAB9AKDM4ETP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198213-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-10-07 | — | — | WO | disclosed |