Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 6/20 | 0.38 |
| ▸ | GABRD | O14764 | 6/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 6/20 | 0.38 |
| ▸ | GABRE | P78334 | 6/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 6/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23902934 | 0.85 | NPC1 (0.51) | NPC1RAB9AGABRA1GABRG2GABRB3 | |
| SCHEMBL20561245 | 0.81 | NPC1 (0.51) | NPC1RAB9AAHRTOP2AGABRP | |
| SCHEMBL29697227 | 0.81 | NPC1 (0.51) | NPC1RAB9AAHRTOP2AGABRP | |
| SCHEMBL23902879 | 0.79 | NPC1 (0.41) | NPC1RAB9A | |
| SCHEMBL23903106 | 0.79 | AHR (0.45) | AHRCDC25BTOP2ACYP1A2CYP1A1 | |
| SCHEMBL23903178 | 0.79 | NPC1 (0.60) | NPC1RAB9AAHRCYP1A2 | |
| SCHEMBL25501209 | 0.79 | RAB9A (0.54) | NPC1RAB9A | |
| SCHEMBL23902877 | 0.79 | NPC1 (0.48) | NPC1RAB9ACDC25BGABRPGABRD | |
| SCHEMBL26227038 | 0.77 | NPC1 (0.62) | NPC1RAB9AAHRGABRPGABRD | |
| SCHEMBL26226874 | 0.76 | NPC1 (0.78) | NPC1RAB9AGABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151026-A1 | MULTI-LAYER BODY FOR DIFFUSE TRANSILLUMINATION | MERCK PATENT GMBH (DE) | 2023-05-18 | — | — | US | disclosed |
| US-20230151026-A1 | MULTI-LAYER BODY FOR DIFFUSE TRANSILLUMINATION | MERCK PATENT GMBH (DE) | 2023-05-18 | — | — | US | disclosed |
| WO-2021198213-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151026-A1 | MULTI-LAYER BODY FOR DIFFUSE TRANSILLUMINATION | DDT, EPCAM, SLC18A3 | NPC1 1782/4885RAB9A 1937/4885AHR 2896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.