⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15160181 | 1.00 | — | — | |
| SCHEMBL9226316 | 1.00 | DNM1 (0.44) | — | |
| SCHEMBL21283103 | 0.88 | — | — | |
| SCHEMBL30110429 | 0.82 | LMNA (0.37) | — | |
| SCHEMBL28999174 | 0.80 | — | — | |
| SCHEMBL28999141 | 0.80 | TRPV1 (0.31) | — | |
| SCHEMBL28999310 | 0.80 | TRPV1 (0.31) | — | |
| SCHEMBL25873632 | 0.80 | — | — | |
| SCHEMBL9226319 | 0.78 | OPRM1 (0.55) | — | |
| SCHEMBL25188306 | 0.77 | DNM1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021201577-A1 | HMG-COA REDUCTASE DEGRADATION INDUCING COMPOUND | UPPTHERA (KR) | 2021-10-07 | — | — | WO | disclosed |