Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 4/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905462 | 0.92 | CFTR (0.36) | CFTRDHODHIDO1CYP2C9HDAC4 | |
| SCHEMBL23905699 | 0.88 | CFTR (0.32) | CFTRIDO1CYP2C9 | |
| SCHEMBL23905327 | 0.87 | CFTR (0.34) | CFTRMAP2K4PTGDR2KCNH2 | |
| SCHEMBL23904788 | 0.86 | DPP4 (0.32) | CFTRIDO1CYP2C9PTGDR2DPP4 | |
| SCHEMBL23905340 | 0.86 | CFTR (0.33) | CFTRDHODHHDAC4HDAC1HDAC6 | |
| SCHEMBL23905333 | 0.84 | MAP2K4 (0.32) | CFTRDHODHHDAC4HDAC1HDAC6 | |
| SCHEMBL23905338 | 0.84 | MAP2K4 (0.32) | CFTRDHODHHDAC4HDAC1HDAC6 | |
| SCHEMBL23196085 | 0.83 | GAA (0.35) | CFTRDHODHPTGDR2 | |
| SCHEMBL23905342 | 0.83 | MAP2K4 (0.34) | CFTRDHODHHDAC4HDAC1HDAC6 | |
| SCHEMBL23905349 | 0.82 | CFTR (0.33) | CFTRDHODHHDAC4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |