Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | G6PD | P11413 | 1/20 | 0.30 |
| ▸ | CTSA | P10619 | 1/20 | 0.30 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23904858 | 0.92 | CTSA (0.32) | MAPTKMT2AALDH1A1L3MBTL1CTSA | |
| SCHEMBL23905381 | 0.91 | CFTR (0.33) | CFTRMAPTSMN1; SMN2KMT2A | |
| SCHEMBL23904783 | 0.88 | MAPT (0.34) | CFTRMAPTSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL23905462 | 0.87 | CFTR (0.36) | CFTRMAP2K4KCNH2PTGDR2CTSA | |
| SCHEMBL23904802 | 0.87 | CFTR (0.36) | CFTRMAP2K4KCNH2PTGDR2 | |
| SCHEMBL23905444 | 0.87 | ALDH1A1 (0.32) | CFTRALDH1A1L3MBTL1GABRA2GABRB2 | |
| SCHEMBL23905330 | 0.87 | CFTR (0.31) | CFTR | |
| SCHEMBL23904768 | 0.86 | CFTR (0.31) | CFTRPTGDR2 | |
| SCHEMBL23905325 | 0.85 | MAPT (0.33) | MAPTSMN1; SMN2KMT2A | |
| SCHEMBL23905731 | 0.83 | MAPT (0.35) | MAPTSMN1; SMN2KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |