Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23904811 | 0.85 | PLK1 (0.46) | PLK1ALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL11962155 | 0.80 | PLK1 (1.00) | PLK1ALDH1A1HPGDKDM4ETDP1 | |
| SCHEMBL9903880 | 0.67 | PKM (0.62) | PLK1ALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL1004083 | 0.67 | RXFP1 (0.68) | PLK1ALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL4143482 | 0.67 | ALDH1A1 (0.77) | PLK1ALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL31650388 | 0.66 | ALDH1A1 (0.60) | PLK1ALDH1A1HPGDLMNARAB9A | |
| SCHEMBL2796317 | 0.65 | PLK1 (0.74) | PLK1ALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL3540758 | 0.65 | CA12 (0.50) | PLK1ALDH1A1TDP1LMNARAB9A | |
| SCHEMBL1464754 | 0.65 | PLK1 (0.57) | PLK1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL642200 | 0.65 | MAPT (0.41) | PLK1ALDH1A1HPGDKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |