Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 6/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.32 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23904820 | 0.80 | PTGS2 (0.46) | — | |
| SCHEMBL23904780 | 0.79 | KDM4E (0.43) | ALDH1A1 | |
| SCHEMBL23905741 | 0.78 | HSD17B2 (0.46) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL23905740 | 0.69 | HSD17B2 (0.45) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8350917 | 0.68 | ACHE (0.38) | ACHEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL23904743 | 0.67 | CCR1 (0.52) | ACHECRHR1ERN1ALDH1A1 | |
| SCHEMBL26567099 | 0.67 | ACHE (0.41) | ACHECRHR1ALDH1A1 | |
| SCHEMBL24028393 | 0.67 | PDE4A (0.34) | PDE4APDE4BPDE4CPDE4DTRPV3 | |
| SCHEMBL15725791 | 0.66 | PDE4A (0.47) | ACHEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30212751 | 0.66 | NPC1 (0.34) | PDE4APDE4BPDE4CPDE4DTRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |