Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | JAK1 | P23458 | 2/20 | 0.39 |
| ▸ | TYK2 | P29597 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | JAK3 | P52333 | 2/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.39 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25116033 | 0.81 | NQO2 (0.45) | HASPINJAK2JAK1TYK2KDR | |
| SCHEMBL12725625 | 0.81 | ALDH1A1 (0.53) | ACHEJAK2JAK1TYK2KDR | |
| SCHEMBL23905531 | 0.76 | CA12 (0.49) | HASPINJAK2JAK1TYK2KDR | |
| SCHEMBL23904743 | 0.76 | CCR1 (0.52) | ACHEALDH1A1CRHR1KDM4ECCR1 | |
| SCHEMBL14595283 | 0.75 | EGFR (0.41) | ACHEJAK2JAK1TYK2KDR | |
| SCHEMBL23958814 | 0.70 | ALDH1A1 (0.46) | ACHEALDH1A1CRHR1SMN1; SMN2CCR1 | |
| SCHEMBL13252142 | 0.70 | JAK1 (0.47) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL16891451 | 0.69 | CYP1A2 (0.46) | HASPINACHEALDH1A1KDM4EPDGFRB | |
| SCHEMBL12775447 | 0.69 | CYP1A2 (0.46) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL13301167 | 0.68 | PSMD14 (0.59) | ALDH1A1KDM4ESMN1; SMN2CCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |