Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PRNP | P04156 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 5/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905909 | 0.86 | ALDH1A1 (0.50) | ALDH1A1PRNPMAPTNPSR1RXFP1 | |
| SCHEMBL23904743 | 0.85 | CCR1 (0.52) | ALDH1A1PRNPMAPTNPSR1RXFP1 | |
| SCHEMBL12074836 | 0.83 | ALDH1A1 (0.42) | ALDH1A1PRNPMAPTNPSR1RXFP1 | |
| SCHEMBL26577804 | 0.79 | PTGS2 (0.44) | ALDH1A1PRNPMAPTNPSR1RXFP1 | |
| SCHEMBL23958607 | 0.79 | ACHE (0.36) | ALDH1A1PRNPMAPTNPSR1RXFP1 | |
| SCHEMBL26762020 | 0.79 | ALDH1A1 (0.40) | ALDH1A1PRNPMAPTNPSR1RXFP1 | |
| SCHEMBL31716007 | 0.78 | CCR1 (0.42) | ALDH1A1PRNPMAPTNPSR1RXFP1 | |
| SCHEMBL14904002 | 0.78 | HSD17B10 (0.43) | ALDH1A1PRNPMAPTNPSR1RXFP1 | |
| SCHEMBL633429 | 0.77 | ALDH1A1 (0.47) | ALDH1A1PRNPMAPTNPSR1RXFP1 | |
| SCHEMBL23195609 | 0.76 | CA12 (0.47) | ALDH1A1PRNPMAPTNPSR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |